镰状细胞病血栓性血小板减少性紫癜的标志性症状是神经系统并发症

IF 1.1 Q4 IMMUNOLOGY Immunopathologia Persa Pub Date : 2023-05-16 DOI:10.34172/ipp.2023.39490
M. Bahadoram, B. Keikhaei, Shahram Rafie, E. Akade, Najmeh Nameh Goshay Fard, Roozbeh Moghaddar
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引用次数: 0

摘要

血栓性血小板减少性紫癜(TTP)是一种微血管疾病,其特点是血管中形成小血块,导致器官损伤和血小板计数低。在镰状细胞病(SCD)中,TTP可由于凝血系统的激活和血管内皮细胞的损伤而发生。TTP在SCD中的重要性在于它可能导致严重和危及生命的并发症,包括中风、肾衰竭和心力衰竭。SCD的TTP早期识别和治疗对于预防这些并发症和改善预后至关重要。在这封信中,我们强调了神经系统并发症在SCD TTP诊断中的重要性。
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Neurological complications as the hallmark symptoms of thrombotic thrombocytopenic purpura in sickle cell disease
Thrombotic thrombocytopenic purpura (TTP) is a type of microangiopathy, which is characterized by the formation of small blood clots in the vessels, leading to organ damage and low platelet count. In sickle cell disease (SCD), TTP can occur due to the activation of the coagulation system and damage to the endothelial cells lining the blood vessels. The importance of TTP in SCD lies in its potential to cause severe and life-threatening complications, including stroke, renal and heart failure. Early recognition and treatment of TTP in SCD are crucial to prevent these complications and improve outcomes. In this letter, we highlighted the significance of neurological complications in the diagnosis of TTP in SCD.
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CiteScore
1.70
自引率
0.00%
发文量
65
审稿时长
3 weeks
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