心血管风险与认知衰老相关的队列差异

IF 0.8 Q4 PSYCHOLOGY, DEVELOPMENTAL GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry Pub Date : 2018-11-21 DOI:10.1024/1662-9647/a000198

P. Karlsson, B. Johansson, I. Skoog, J. Skoog, L. Rydén, Valgeir Thorvaldsson

{"title":"心血管风险与认知衰老相关的队列差异","authors":"P. Karlsson, B. Johansson, I. Skoog, J. Skoog, L. Rydén, Valgeir Thorvaldsson","doi":"10.1024/1662-9647/a000198","DOIUrl":null,"url":null,"abstract":"Aim: To investigate birth cohort differences in associations between cardiovascular risk and fluid cognition between the age of 70 and 79. Method: Data were drawn from representative population-based cohort samples (H70), born 1901–1902, 1906–1907, and 1930, measured at ages 70, 75, and 79 on fluid cognitive measures (spatial ability and logical reasoning). The Framingham Risk Score (FRS), derived from office-based nonlaboratory predictors (age, sex, systolic blood pressure, BMI, smoking, diabetes status), was used to measure cardiovascular risk. Multiple-group latent growth curve models were fitted to the data. Findings: Estimates revealed small associations between the FRS and fluid cognition. These associations were slightly reduced in the 1930 cohort. Conclusion: Findings suggest diminishing adverse effects of cardiovascular risk on cognitive aging in cohorts born later.","PeriodicalId":45525,"journal":{"name":"GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2018-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Cohort Differences in the Association of Cardiovascular Risk and Cognitive Aging\",\"authors\":\"P. Karlsson, B. Johansson, I. Skoog, J. Skoog, L. Rydén, Valgeir Thorvaldsson\",\"doi\":\"10.1024/1662-9647/a000198\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aim: To investigate birth cohort differences in associations between cardiovascular risk and fluid cognition between the age of 70 and 79. Method: Data were drawn from representative population-based cohort samples (H70), born 1901–1902, 1906–1907, and 1930, measured at ages 70, 75, and 79 on fluid cognitive measures (spatial ability and logical reasoning). The Framingham Risk Score (FRS), derived from office-based nonlaboratory predictors (age, sex, systolic blood pressure, BMI, smoking, diabetes status), was used to measure cardiovascular risk. Multiple-group latent growth curve models were fitted to the data. Findings: Estimates revealed small associations between the FRS and fluid cognition. These associations were slightly reduced in the 1930 cohort. Conclusion: Findings suggest diminishing adverse effects of cardiovascular risk on cognitive aging in cohorts born later.\",\"PeriodicalId\":45525,\"journal\":{\"name\":\"GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2018-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1024/1662-9647/a000198\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PSYCHOLOGY, DEVELOPMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"GeroPsych-The Journal of Gerontopsychology and Geriatric Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1024/1662-9647/a000198","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PSYCHOLOGY, DEVELOPMENTAL","Score":null,"Total":0}

引用次数: 2

摘要

目的：研究70岁至79岁之间心血管风险和液体认知之间的出生队列差异。方法：数据来自1901年-1902年、1906年-1907年和1930年出生的代表性人群队列样本（H70），在70岁、75岁和79岁时测量流体认知测量（空间能力和逻辑推理）。Framingham风险评分（FRS）来源于基于办公室的非流产预测因素（年龄、性别、收缩压、BMI、吸烟、糖尿病状况），用于测量心血管风险。数据拟合了多组潜在生长曲线模型。研究结果：估计显示FRS和流体认知之间有很小的关联。这些关联在1930年的队列中略有减少。结论：研究结果表明，在出生较晚的队列中，心血管风险对认知衰老的不良影响正在减少。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Cohort Differences in the Association of Cardiovascular Risk and Cognitive Aging

Aim: To investigate birth cohort differences in associations between cardiovascular risk and fluid cognition between the age of 70 and 79. Method: Data were drawn from representative population-based cohort samples (H70), born 1901–1902, 1906–1907, and 1930, measured at ages 70, 75, and 79 on fluid cognitive measures (spatial ability and logical reasoning). The Framingham Risk Score (FRS), derived from office-based nonlaboratory predictors (age, sex, systolic blood pressure, BMI, smoking, diabetes status), was used to measure cardiovascular risk. Multiple-group latent growth curve models were fitted to the data. Findings: Estimates revealed small associations between the FRS and fluid cognition. These associations were slightly reduced in the 1930 cohort. Conclusion: Findings suggest diminishing adverse effects of cardiovascular risk on cognitive aging in cohorts born later.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊