基孔肯雅病毒关节炎模拟血清阴性类风湿性关节炎

Q3 Medicine Revmatologiia (Bulgaria) Pub Date : 2019-12-01 DOI:10.35465/27.4.2019.pp49-54
Вл. Бояджиева, Н. Стоилов, Е. Куртева, Р. Стоилов, V. Boyadzhieva, N. Stoilov, E. Kurteva, R. Stoilov
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引用次数: 0

摘要

基孔肯雅病毒(CHIKV)是一种通过埃及伊蚊和白纹伊蚊传播的致关节炎虫媒病毒感染。临床表现多种多样,从轻度流动、几乎无症状到典型的发烧、多肌痛、多关节痛和关节炎。世界的全球化正在增加感染在已知流行地区以外传播的机会。这就需要进行广泛的鉴别诊断,尤其是在类似类风湿性关节炎等炎症性关节疾病的病例中。所介绍的临床病例是一名从马尔代夫旅行回来的患者,据我们所知,这是保加利亚共和国的首例病例,是在详细参考文献后确定的。风湿病学家,即使是在非CHIKV流行地区,在评估持续六周以上的对称性多关节炎时,也应该考虑CHIKV,尤其是在前往CHIKV流行区的记忆可能在不久的将来扩大的情况下。然而,证明基孔肯雅病毒抗体呈阳性是风湿病学家区分这两种疾病的主要帮助。
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Chikungunya viral arthritis mimicking seronegative rheumatoid arthritis
Chikungunya virus (CHIKV) is an arthritogenic arbovirus infection transmitted through the mosquitoes Aedes aegypti and Aedes albopictus. The clinical picture is diverse - from mildly flowing, almost asymptomatic forms to characteristic episodes of fever, polymyalgia, polyarthralgia, and arthritis. Globalization of the world is increasing the chances of infection spreading outside known endemic areas. This necessitates a broad differential diagnosis, especially in cases that mimic inflammatory joint diseases such as rheumatoid arthritis. The presented clinical case is of a patient who has returned from a trip to the Maldives and is the first in the Republic of Bulgaria as far as we know, and is established after a detailed literature reference has been made. Rheumatologists, even in non-CHIKV-endemic regions, should consider CHIKV in their evaluation of symmetric polyarthritis lasting above six weeks, especially in case of anamnesis for a trip to the endemic regions to CHIKV that are likely to expand in the near future. However, demonstrating positive antibodies to the Chikungunya virus is the rheumatologist‘s primary help in distinguishing the two diseases.
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来源期刊
Revmatologiia (Bulgaria)
Revmatologiia (Bulgaria) Medicine-Rheumatology
CiteScore
0.30
自引率
0.00%
发文量
21
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