抗逆转录病毒治疗(ART)患者滞留:喀麦隆雅温得治疗中心的经验

M. Denis, Shey Budi Ernest
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摘要

尽管针对艾滋病毒/艾滋病的抗逆转录病毒治疗扩大方案取得了成就,但保留仍然是一个挑战。实现可持续发展目标的“90-90-90”艾滋病毒目标取决于能否坚持。尽管无限期保留患者护理很重要,但喀麦隆仍有33%的艾滋病毒患者无法进行随访,从而影响了扩大规模的举措。本研究分析了治疗中心接受ART治疗的患者的数据以及相关的随访损失因素,并提出了解决这些问题的措施。这项研究是对选定的HIV/AIDS TCs数据的回顾性分析。在获得同意后,由参与的TC填写问卷。使用SPSS对收集的数据进行分析,并将数据表示为条形图和直方图。七名TC中有五名参与,参与率为71.4%。在12165名患者中,11852名(97.4%)为成年人(28.0%为男性,69.4%为女性),313名(2.6%)为儿童。共有232人(1.9%)失访,38人在6至12个月内死亡。随访失败的可能原因包括治疗和依从性咨询不力、无知、污名化、经济困难以及传统和宗教信仰。所有TC都报告说,由于距离、工作性质和过度拥挤,他们被转移到中心内外。其他研究证实了从诊断到长期保留的整个护理过程中对流失率的担忧。这种消耗损害了扩大抗逆转录病毒疗法的收益,导致健康结果较差,浪费了有限的资源。因此,建立持续的咨询和教育服务,解决社会决定因素,并建立在社会支持因素的基础上,提供了提高保留率的措施。关键词:保留率、抗逆转录病毒治疗、治疗、随访损失。
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Patient retention on anti-retroviral therapy (ART): Experience of treatment centres (TCs) in Yaounde, Cameroon
Despite the achievements of Anti-retroviral Treatment (ART) scale-up programmes for HIV/AIDS, retention remains a challenge. Achievements of the “90-90-90” HIV targets for the sustainable development goals hinges on adherence. Despite the importance of indefinite retention of patients in care, 33% of HIV patients in Cameroon are still lost-to-follow-up, thereby compromising scale-up initiatives. This study analyses data of patients on ART in Treatment Centres (TCs) and the associated loss-to-follow-up factors and proposes measures to address them. This research was a retrospective analysis of data from selected HIV/AIDS TCs. After obtaining consent, questionnaires were filled by participating TCs. Collected data were analysed using SPSS and figures were expressed as bar charts, and histograms. Five out of seven TCs participated, giving a participation rate of 71.4%. Of the 12,165 patients, 11,852 (97.4%) were adults (28.0% males and 69.4% females) while 313 (2.6%) were children. A total of 232 (1.9%) were lost-to-follow-up and 38 died within six to twelve months. Possible causes of loss-to-follow-up included poor treatment and adherence counselling, ignorance, stigmatisation, financial hardship and traditional and religious beliefs. All TCs reported transfer into and out of their centre, caused by distance, nature of job, and overcrowding. Concerns of attrition rates throughout the continuum of care from diagnosis to long-term retention are corroborated by other studies. Such attrition compromises gains from ART scale-up, leading to poorer health outcomes and wastage of limited resources. Therefore, instituting sustained counselling and education services, addressing social determinants and building on social support factors provide measures to improve retention Key words: Retention, anti-retroviral therapy, treatment, loss-to-follow-up.
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