印度尼西亚万隆哈桑·萨迪金医生总医院的蛇咬伤和血清抗Bisa Ular (SABU)抗蛇毒血清的效果:2015-2019年概述期

Sharon Noor Alya, Enny Rochmawaty, Achadiyani, M. H. Bashari, H. Soedjana
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引用次数: 0

摘要

背景:蛇咬伤被认为是一个全球性的卫生问题,特别是在东南亚地区。然而,关于印度尼西亚蛇咬伤病例的数据仍然非常有限。本研究旨在探讨毒蛇咬伤病例及血清抗斜视(SABU)抗蛇毒血清在治疗非现有SABU抗蛇毒血清制剂中所示蛇类所致毒蛇咬伤中的作用。方法:采用横断面研究设计的分析描述性方法,于2021年对万隆哈桑·萨迪金医生总医院2015年至2019年诊断为蛇咬伤的63例患者的医疗记录进行总抽样。收集患者的特点、临床表现以及使用或不使用SABU抗蛇毒血清治疗后蛇种与结果的相关性。结果:63例患者中,男性占79%,平均年龄39岁。56例患者在事件发生后24小时内到达急诊室(89%)。大多数病例被分类为2级(41%),上肢常被咬伤,身体部位(64%)。水肿(83%)是最常见的表现。对特定蛇类施用抗蛇毒血清与所述结果之间没有相关性(p=0.053),这意味着SABU抗蛇毒血清可能是治疗更多类型蛇咬伤的有效替代方案。结论:蛇咬伤在男性中最常见,攻击上肢,分类为2级水肿。SABU抗蛇毒血清与爪哇吐舌眼镜蛇、带状金环蛇和马来亚蝮蛇造成的结果相似。
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Snakebites and the Effect of Serum Anti Bisa Ular (SABU) Antivenom at Dr. Hasan Sadikin General Hospital Bandung, Indonesia: an Overview Period 2015–2019
Background: Snakebite is considered a global health issue, especially in the Southeast Asian region. However, data regarding snakebite cases in Indonesia are still very limited. This study aimed to explore the venomous snakebite cases and the serum anti bisa ular (SABU) antivenom effect in treating venomous snakebite caused by other than the snake species indicated in currently available SABU antivenom formulas. Methods: The analytical descriptive method with a cross-sectional study design was conducted in 2021 using a total sampling from the medical records of 63 patients diagnosed with snakebite at Dr. Hasan Sadikin General Hospital Bandung from 2015 to 2019. Characteristics of patients, clinical manifestation, and correlation between snakes species and outcomes after treatment with or without administration of SABU antivenom were collected. Results: Out of 63 patients, males (79%) were predominant with an average age of 39 years. Fifty-six patients arrived at the Emergency Room less than 24 hours after the occurrence (89%). Most cases were categorized as grade 2 (41.%) where the upper extremities were commonly bitten the body area (64%). Edema (83%) was the most common manifestation. There was no correlation between snake antivenom administered to a specific snake species and the stated outcome (p=0.053), meaning that SABU antivenom might be an effective alternative to treat more types of snakebites. Conclusions: Snakebites are most common in males, attack the upper extremities, categorized as grade 2 with edema. Administration of SABU antivenom provides the similar outcome compared to the group caused by the Javan spitting cobra, Banded krait, and Malayan pit viper.
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