儿童肺、支气管肿瘤手术治疗的新途径

Q4 Biochemistry, Genetics and Molecular Biology International Journal of Biology and Biomedical Engineering Pub Date : 2021-07-30 DOI:10.46300/91011.2021.15.37
O. V. Bilokon, E. Shaida, P. Sokur, B. O. Kravchuk
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引用次数: 0

摘要

今天,寻找新的,更好的手术治疗肿瘤和器官保存的方法和视频辅助手术越来越受欢迎。本研究的目的是改善使用高频活组织焊接(HF LTW)手术治疗儿童原发性和继发性(转移性)肺肿瘤的效果,以提高治疗效果。本研究的新颖之处在于扩展了新研究方法的知识,以提高相对于以往研究的化疗和放疗方法的生存能力。本文分析了2002年至2018年收治的原发性和转移性肺肿瘤患儿103例,其中良恶性肺肿瘤34例,转移性支气管和肺部病变69例。17例患者被诊断为良性肺肿瘤。恶性肿瘤17例,其中肺类癌11例。支气管和肺部转移性病变最常发生在骨肉瘤(28例)和肾母细胞瘤(17例)。34例原发性肿瘤患儿中,37例接受手术治疗。大多数情况下,非典型切除16例(43.3%),特别是类癌7例(43.8%)和错构瘤4例(25%)。对于转移性病变,在大多数情况下,进行相同的切除。在58例手术中,25例(43%)为骨肉瘤,15例(26%)为肾母细胞瘤。29例良性和恶性原发肿瘤患者使用了HF LTW方法,62例(73%)肺转移手术中使用了HF LTW方法切除肿瘤、血管凝固和肺组织密封。在小儿支气管、肺部良、恶性及转移性病变中,采用不同方向、不同体积的高频LTW可有效地进行手术。
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New Approaches to the Surgical Treatment of Lung and Bronchial Tumors in Children
Today, it is relevant to search for new, better methods of surgical treatment of tumors and organ-preserving and video-assisted surgery is gaining more and more popularity. The aim of the study was to improve the results of surgical treatment of children with primary and secondary (metastatic) lung tumors using high-frequency live tissue welding (HF LTW) in order to increase the treatment effectiveness. Novelty of the study lies in the expanding the knowledge of the new researched method, for enhancement of survivability relatively to chemotherapy and radiation methods, that are studied in the previous works. Advantages of the introduced method are bloodless, fast, low traumatic operations 103 case reports in children with primary and metastatic lung tumors were analyzed, including 34 patients with benign and malignant lung tumors and 69 children with metastatic bronchial and pulmonary lesions undergoing treatment from 2002 to 2018 were examined. Benign lung tumors were diagnosed in 17 patients. Malignant tumors were observed in 17 patients, including 11 lung carcinoid tumors. Metastatic bronchial and pulmonary lesions most often occurred with osteosarcoma (28) and nephroblastoma (17). In 34 children with primary tumors, 37 were undergone surgical interventions. Most often, atypical resection was used – 16 (43.3%), in particular, with carcinoid – in 7 (43.8%) patients and with hamartoma – in 4 (25%) patients. In metastatic lesions, in most cases, the same resection was performed. From 58 resections 25 (43%) were performed for osteosarcoma and 15 (26%) for nephroblastoma. The HF LTW method was used in 29 patients for benign and malignant primary tumors and in 62 (73%) surgical procedures for lung metastases to remove a tumor, vascular coagulation and sealing of the lung tissue. Using HF LTW surgical operations of different directions and volumes can be performed effectively in benign, malignant and metastatic bronchial and pulmonary lesions in children.
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来源期刊
International Journal of Biology and Biomedical Engineering
International Journal of Biology and Biomedical Engineering Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
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期刊介绍: Topics: Molecular Dynamics, Biochemistry, Biophysics, Quantum Chemistry, Molecular Biology, Cell Biology, Immunology, Neurophysiology, Genetics, Population Dynamics, Dynamics of Diseases, Bioecology, Epidemiology, Social Dynamics, PhotoBiology, PhotoChemistry, Plant Biology, Microbiology, Immunology, Bioinformatics, Signal Transduction, Environmental Systems, Psychological and Cognitive Systems, Pattern Formation, Evolution, Game Theory and Adaptive Dynamics, Bioengineering, Biotechnolgies, Medical Imaging, Medical Signal Processing, Feedback Control in Biology and Chemistry, Fluid Mechanics and Applications in Biomedicine, Space Medicine and Biology, Nuclear Biology and Medicine.
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