{"title":"电力在血管生成中的作用","authors":"O. Szász, G. Szigeti, A. Szász, Z. Benyó","doi":"10.4236/ojbiphy.2018.82005","DOIUrl":null,"url":null,"abstract":"The role of electrical forces in angiogenesis is widely studied. The electric field (EF) induces polarization of the endothelial cells, and in this way, it is a morphogen in angiogenesis. Additional to the polarization, it may build up by newborn cells in the process of cellular fission. Due to the weak direct experimental results on the transitions of endothelial cells, we used an analogy to these epithelial transitions. This involved using the injury current, which induces oriented cell migration and morphological arrangement in wound healing. The injury-current considerations are applied for malignant proliferation as well.","PeriodicalId":59528,"journal":{"name":"生物物理学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Role of Electrical Forces in Angiogenesis\",\"authors\":\"O. Szász, G. Szigeti, A. Szász, Z. Benyó\",\"doi\":\"10.4236/ojbiphy.2018.82005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The role of electrical forces in angiogenesis is widely studied. The electric field (EF) induces polarization of the endothelial cells, and in this way, it is a morphogen in angiogenesis. Additional to the polarization, it may build up by newborn cells in the process of cellular fission. Due to the weak direct experimental results on the transitions of endothelial cells, we used an analogy to these epithelial transitions. This involved using the injury current, which induces oriented cell migration and morphological arrangement in wound healing. The injury-current considerations are applied for malignant proliferation as well.\",\"PeriodicalId\":59528,\"journal\":{\"name\":\"生物物理学期刊(英文)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"生物物理学期刊(英文)\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.4236/ojbiphy.2018.82005\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"生物物理学期刊(英文)","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.4236/ojbiphy.2018.82005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The role of electrical forces in angiogenesis is widely studied. The electric field (EF) induces polarization of the endothelial cells, and in this way, it is a morphogen in angiogenesis. Additional to the polarization, it may build up by newborn cells in the process of cellular fission. Due to the weak direct experimental results on the transitions of endothelial cells, we used an analogy to these epithelial transitions. This involved using the injury current, which induces oriented cell migration and morphological arrangement in wound healing. The injury-current considerations are applied for malignant proliferation as well.
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