大鼠盲肠浆液、LPS和大肠杆菌诱导的全身炎症反应综合征(SIRS)心脏组织氧化应激和炎症生物标志物分析

S. Jana
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引用次数: 0

摘要

本研究旨在评估在Sprague-Dawley大鼠Cecal淤浆、LPS和大肠杆菌诱导的全身炎症反应综合征(SIRS)模型上,用Biofield Energy Treated Proprietary Test Formula和Biofield Energy treatment本身治疗动物后,心脏组织中的抗氧化和抗炎生物标志物。在本实验中,与G4组相比,不同的抗氧化剂生物标志物,如髓过氧化物酶(MPO)、超氧化物歧化酶(SOD)、脂质过氧化物酶(LPO)和促炎细胞因子,如肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、巨噬细胞炎症蛋白-2(MIP-2)和基质金属肽酶G8和G9组。总之,这些数据表明了生物场能量治疗试验制剂和生物场能量处理本身的抗氧化和抗炎潜力,以及对动物的各种炎症条件的预防措施,这些条件可能有益于各种类型的全身炎症疾病,特别是败血症、创伤、感染性休克或任何类型的心脏损伤。因此,结果显示,与疾病对照组相比,预防性生物场能量治疗组本身和/或生物场能量处理测试制剂组(即G6、G7、G8和G9)的炎症相关疾病进展及其并发症/症状显著减缓。
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Oxidative Stress and Inflammatory Biomarkers Analysis of Biofield Treated Proprietary Test Formulation in Heart Tissues in Cecal Slurry, LPS and E. Coli-induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats
The study was aimed to evaluate the antioxidant and anti-inflammatory biomarkers in heart tissues after treatment with the Biofield Energy Treated Proprietary Test Formulation and Biofield Energy Treatment per se to the animals on Cecal Slurry, LPS and E. coli -induced systemic inflammatory response syndrome (SIRS) model in Sprague Dawley rats. In this experiment, different antioxidants biomarkers such as myeloperoxidase (MPO), superoxide dismutase (SOD), lipid peroxidase (LPO) and proinflammatory cytokines such as tumor necrosis factor-α (TNF- α), interleukin-6 (IL-6), macrophage inflammatory protein-2 (MIP-2), and matrix metallopeptidase G8, and G9 groups, respectively as compared to the G4 group. Altogether, the data imply the antioxidant and anti-inflammatory potential of the Biofield Energy Treated test formulation and Biofield Energy Treatment per se along with preventive measure on the animal with respect to various inflammatory conditions that might be beneficial various types of systemic inflammatory disorders specially sepsis, trauma, septic shock or any types of cardiac injuries. Therefore, the results showed the significant slowdown the inflammation-related disease progression and its complications/symptoms in the preventive Biofield Energy Treatment group per se and/or Biofield Energy Treated Test formulation groups (viz. G6, G7, G8, and G9) comparatively with the disease control group.
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