不同遗传结构下非参数基因组选择方法的比较研究

IF 1 4区 生物学 Q3 PLANT SCIENCES Indian Journal of Genetics and Plant Breeding Pub Date : 2020-11-30 DOI:10.31742/ijgpb.80.4.4
Neeraj Budhlakoti, Anil Rai, D. Mishra, S. Jaggi, Mukesh Kumar, A. Rao
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引用次数: 2

摘要

基因组选择(GS)是当今最普遍的方法,可以获得被研究个体的遗传优势。它根据自己的遗传优势为下一个繁殖周期选择候选者。在过去的十年里,GS已经成功地应用于各种植物和动物研究。已经提出了几种参数统计模型,并在各种GS研究中成功使用。然而,当我们有非加性的遗传结构时,参数方法的性能变得非常差。在这种情况下,非参数方法的性能通常是令人满意的,因为这些方法不需要严格的统计假设。本文介绍了几种最常用的非参数方法对复杂遗传结构的比较性能,即非加性方法,使用在不同遗传力水平和不同群体规模组合下生成的模拟数据集。在几种非参数方法中,SVM在一系列遗传结构中表现出色。
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Comparative study of different non-parametric genomic selection methods under diverse genetic architecture
Genomic Selection (GS) is the most prevalent method in today’s scenario to access the genetic merit of individual under study. It selects the candidates for next breeding cycle on the basis of its genetic merit. GS has successfully been used in various plant and animal studies in last decade. Several parametric statistical models have been proposed and being used successfully in various GS studies. However, performance of parametric methods becomes very poor when we have non additive kind of genetic architecture. In such cases, generally performance of non-parametric methods are quite satisfactory as these methods do not require strict statistical assumptions. This article presents comparative performance of few most commonly used non-parametric methods for complex genetic architecture i.e. non-additive, using simulated dataset generated at different level of heritability and varying combination of population size. Among several non-parametric methods, SVM outperformed across a range of genetic architecture.
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来源期刊
CiteScore
1.80
自引率
10.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Advance the cause of genetics and plant breeding and to encourage and promote study and research in these disciplines in the service of agriculture; to disseminate the knowledge of genetics and plant breeding; provide facilities for association and conference among students of genetics and plant breeding and for encouragement of close relationship between them and those in the related sciences; advocate policies in the interest of the nation in the field of genetics and plant breeding, and facilitate international cooperation in the field of genetics and plant breeding.
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