2019年海得拉巴一家三级护理医院住院人群中的长期冠状病毒疾病后遗症

S. Bala, S. Darivemula, Venkatesham Animalla, R. Bandaru
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引用次数: 0

摘要

在2019冠状病毒大流行期间,许多人通常会遇到长期新冠肺炎。最好通过与2019年急性冠状病毒病(新冠肺炎)一致的病史进行诊断,然后长期康复。已经尝试在临床上招募长期新冠肺炎的后遗症,并评估其风险因素。我院收治的新冠肺炎确诊患者在急性症状感染3-12周后和慢性症状感染12周后,通过预先设计的关于其表现的问卷表询问其感染后的持续症状,并每月随访6个月。我们的研究共纳入152名患者,发现与神经系统(72.2%)、呼吸系统(64.7%)和肌肉骨骼系统(61.4%)相关的急性长期新冠肺炎症状最常见。慢性症状主要包括肌肉骨骼(63.1%),其次是疲劳(43.4%)和神经系统(29.6)表现。急性后新冠肺炎症状的风险因素估计显示,女性的风险增加,比值比(OR)(和95%置信区间)(OR)为2.412(1.239-4.692),久坐生活方式OR为1.775(1.345-2.762),体重指数(BMI)>23或3.877(1.613-16.144),合并症OR为2.526(1.277-4.997)。同样,对慢性新冠肺炎症状的风险因素估计显示,女性的风险增加,OR为1.879(0.952–3.709),久坐生活方式OR为5.091(2.853–9.085),BMI>23 OR为2.082(1.005–4.134),合并症OR为1.851(0.925–3.705)。注意到的长期新冠肺炎症状主要与肌肉骨骼疾病、神经系统、呼吸系统和疲劳有关。这一列举将有助于我们进一步将这一长期新冠肺炎实体纳入初级保健层面的常规设置中,用于预防策略。
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Long Coronavirus Disease 2019 Sequel among Cohorts Admitted to a Tertiary Care Hospital, Hyderabad
Long COVID is commonly encountered by many individuals during the coronavirus 2019 pandemic. It is best diagnosed by a history consistent with acute coronavirus disease 2019 (COVID-19) followed by a prolonged recovery. An attempt has been made to enlist the sequel of long COVID clinically and to assess their risk factors. Confirmed COVID-19 patients admitted to our hospital were enquired about their persistent symptoms following infection after 3– 12 weeks for acute symptoms and after 12 weeks for chronic symptoms through the predesigned questionnaire schedule about their manifestations and followed up every month for 6 months. A total of 152 patients were included in our study and found acute long COVID symptoms related to neurological (72.2%), respiratory (64.7%), and musculoskeletal (61.4%) system being most commonly affected. Chronic symptoms were comprised predominantly musculoskeletal (63.1%) followed by fatigue (43.4%) and neurological (29.6) manifestations. Risk factors estimate of postacute COVID-19 symptoms showed that females had increased risk with odds ratio (OR) (and 95% confidence intervals) (OR) of 2.412 (1.239–4.692), sedentary lifestyle OR 1.775 (1.345–2.762), body mass index (BMI) >23 OR 3.877 (1.613–6.144), and presence of comorbidities OR 2.526 (1.277–4.997). Similarly, risk factor estimate of Postchronic COVID-19 symptoms showed that females had increased risk with OR 1.879 (0.952–3.709), sedentary lifestyle OR 5.091 (2.853–9.085), BMI >23 OR 2.082 (1.005–4.134), and presence of comorbidities OR 1.851 (0.925–3.705). Long COVID symptoms noted were mainly related to musculoskeletal disorders, neurological, respiratory, and fatigue. This enumeration will help us to bring the further pathway to include this long COVID entity for preventive strategies in our regular setup at the primary care level.
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审稿时长
16 weeks
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