精准医疗在新冠肺炎管理中的应用

Q3 Agricultural and Biological Sciences Novel Research in Microbiology Journal Pub Date : 2021-08-01 DOI:10.21608/nrmj.2021.190247
Shrikant Verma, M. Abbas, Sushma Verma, Aliya Abbas Rizvi, Almas Khan, Syed Tasleem Raza, F. Mahdi
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引用次数: 0

摘要

精准用药的理念正在逐渐变得出名。大量信息的利用,基因组学和其他“组学”,如代谢组学;蛋白质组学和转录组学;可能很快就会让个性化药物的幻想变成现实。精确药物治疗的最新进展允许根据患者的特定分子解释调整各种病理学中的有用方法。精准用药(PM)代表了一种关于感染检测的新思维方式;预防和治疗。PM场地在一种新出现的新冠病毒毒性疾病中的使用越来越突出。各种发现表明,严重急性呼吸系统疾病COVID-2(SARS-CoV-2)是2019冠状病毒病(新冠肺炎)的罪魁祸首,该病导致了一系列限制病毒传播的程序,影响了人们的习惯和生活方式。根据病毒基因组测序,严重急性呼吸系统综合征冠状病毒2型刺突蛋白使用血管紧张素转换酶2(ACE2)作为其特定受体,该酶建立在人类肺部纤毛上皮细胞上。在这种特殊情况下;精准用药是一种综合性的有益方法,它考虑了传统因素(即年龄、性别、临床综合因素),就像产生遗传品质和与自然成分的联系一样,以个性化预防;诊断、治疗和预后。这篇综述的目的是总结精准医学在新冠肺炎管理中的影响19。
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A perspective of precision medicine in the management of COVID-19
The idea of precision medication is turning out progressively to be famous. The utilization of enormous information, genomics and other "omics" like metabolomics; proteomics and transcriptomics; could soon cause the fantasy of personalized medication to turn into a reality. The most recent advancements in precision medication permit the adjustment of helpful approaches in various pathologies based on the particular molecular interpretation of the patient. Precision medication (PM) represents a new way of thinking about infection detection; prevention and treatment. The use of PM grounds in an emerging COVID virulent disease is becoming more prominent. Various discoveries revealed that severe acute respiratory disorder COVID-2 (SARS CoV-2) is accountable for the Coronavirus disease -2019 (COVID-19), which caused slew of procedures to restrict viral spread, affecting people's habits and lifestyles. According to the viral genomic sequencing, the SARS-CoV-2 spike protein uses angiotensin-converting enzyme 2 (ACE2), which is established on the ciliated epithelial cells of the human lungs as its particular receptor. In this specific situation; precision medication is an integrative helpful methodology that thinks about conventional elements (i.e. age, sex, clinical aggregate), just as arising hereditary qualities and connections with natural components, to individualize prevention; diagnosis, treatments and prognosis. The aim of this review was to summarize how precision medicine is impactful in the management of COVID19.
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来源期刊
CiteScore
1.40
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发文量
16
审稿时长
4 weeks
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