近红外光谱技术在颈动脉内膜切除术中的应用

Lixia Li, Lei Zhao, Tianlong Wang, Wei Xiao, Yi An, Pi-Shan Wang
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引用次数: 0

摘要

颈动脉内膜切除术(CEA)是预防颈动脉狭窄症状和无症状患者中风的有效治疗方法。然而,颈动脉交叉夹闭过程中的脑灌注不足可能导致围手术期脑卒中,神经监测有助于检测脑缺血,从而采取相关的治疗措施。近红外光谱法(NIRS)测量反映颅内灌注的局部脑血氧饱和度(rSO2)的变化,以确定脑缺血的发生。其技术简单、无创,可在CEA期间进行连续实时监测。本文结合近年来国内外最新研究,分析了CEA术中各种神经监测技术的实用性和准确性。本文重点介绍CEA的各种口内神经监测技术,NIRS与其他监测技术的相关性,以及NIRS在预测术中缺血和术后高灌注中的作用,以进一步了解NIRS的临床作用,从而促进其在临床中的应用。关键词:颈动脉内膜切除术;近红外光谱;脑缺血;脑血氧计;脑积水综合征
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Application of near-infrared spectroscopy in carotid endarterectomy
Carotid endarterectomy (CEA) is effective treatment approach to prevent stroke in both symptomatic and asymptom-atic patients with carotid artery stenosis. However, cerebral hypoperfusion during carotid artery cross-clamping may lead to periopera-tive stroke, and nerve monitoring can be helpful in detection of cerebral ischemia, so as to take relevant treatment therapy. Near-infra-red spectroscopy (NIRS) measures the changes of regional cerebral oxygen saturation (rSO2) which can reflect intracranial perfusion, so as to determine the occurrence of cerebral ischemia. Its technique is simple and non-invasive, and can perform continuous and re-al-time monitoring during CEA. In this paper, the practicality and accuracy of various intraoperative neuro-monitoring techniques for CEA were analyzed in combination with the latest domestic and foreign studies in recent years. This paper focuses on various intraoper-ative neuro-monitoring techniques in CEA, the correlation between NIRS and other monitoring techniques, and the role of NIRS in pre-dicting intraoperative ischemia and postoperative hyperperfusion, which can further understand the clinical role of NIRS, so as to facili-tate its application in clinical setting. Key words: Carotid endarterectomy; Near-infrared spectroscopy; Cerebral ischemia; Cerebral oximetry; Cerebral hy-perperfusion syndrome
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