因恶性肿瘤而接受重大选择性外科手术的泌尿科患者虚弱综合征的患病率

Cyprian Michalik, K. Juszczak, A. Stelmach, J. Kenig, T. Drewa
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引用次数: 0

摘要

老年泌尿外科患者群体不断扩大。大多数泌尿外科手术都是在这一组进行的。目前的术前评估模型在年轻患者中有效,但在老年人中无效。虚弱综合征已被证实是一个有效的风险分层工具在许多外科设置。它可以使用多种筛查工具进行诊断,但唯一客观的工具是综合老年评估(CGA)。然而,它耗时,困难,据我们所知,还没有在波兰泌尿科患者中尝试过。材料和方法我们使用CGA和筛查试验评估了因恶性肿瘤而接受手术的老年泌尿科患者的虚弱患病率。共有68例65岁以上符合择期泌尿外科大手术条件的患者接受了术前评估,包括使用传统工具(病史、体格检查、ASA评分)、CGA和虚弱筛查试验。采用Clavien-Dindo评分法评估术后30天并发症发生率。结果患者平均年龄71岁。最常见的手术是根治性前列腺切除术(47.1%)、根治性肾切除术(36.6%)和根治性膀胱切除术(11.8%)。使用CGA的虚弱患病率为39.7%,使用筛查试验的虚弱患病率为4.4-10.3%。使用CGA时,体弱个体的并发症发生率明显较高。结论老年泌尿科患者普遍存在虚弱。CGA是一种耗时但可靠的诊断虚弱综合征和预测并发症的工具。筛选试验可用于选择应该接受CGA的患者,但其预测价值较低。
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Prevalence of frailty syndrome in urological patients undergoing major elective surgical procedure due to malignancy
Introduction The group of elderly urological patients is growing. A majority of urological operations is performed in this group. The current model of preoperative assessment is developed to be effective in younger groups of patients but not in the elderly. Frailty syndrome has been confirmed to be an effective risk stratification tool in many surgical settings. It can be diagnosed using a variety of screening tools, but the only objective tool is comprehensive geriatric assessment (CGA). However it is time consuming, difficult and to our best knowledge, has not been attempted in Polish urological patients. Material and methods We assessed the prevalence of frailty in elderly urological patients undergoing surgery due to malignancy using CGA and screening tests. A total of 68 patients over 65 years of age qualified to elective major urological surgery underwent the preoperative assessment including use of traditional tools (medical history, physical examination, ASA score), CGA and frailty-screening tests. The 30-day postoperative complications rate using the Clavien-Dindo scale was also evaluated. Results The mean age of patients was 71 years. The most common procedures were radical prostatectomy (47.1%), radical nephrectomy (36.6%) and radical cystectomy (11.8%). The prevalence of frailty was 39.7% using CGA and 4.4–10.3% using screening tests. The complication rate was significantly higher in frail individuals when using CGA. Conclusions Frailty is common in urological elderly patients. The CGA is a time-consuming but reliable tool to diagnose frailty syndrome and predict complications. Screening tests can be useful for selecting patients who should undergo CGA but their predictive value is low.
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