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Surgical outcomes of low-power thulium laser enucleation of prostates >80 g. One-year of follow-up. 低功率铥激光前列腺除核>80 g的手术效果。一年的随访。
Pub Date : 2023-01-01 Epub Date: 2023-07-12 DOI: 10.5173/ceju.2023.50
Samer Morsy, Islam Kamal, Alaa Meshref, Mostafa Abdel-Mohsen, Mahmoud Abdel-Hakim, Ahmed Yehia

Introduction: The aim of this study was to assess the effectiveness of low-power thulium (30 W) and the duration necessary to eliminate adenomas at the level of the surgical capsule, as well as its impact on postoperative urinary and sexual function.

Material and methods: Patients with symptomatic benign prostatic hyperplasia (BPH), who had ThuLEP between December 2019 and March 2022 and had a prostate size >80 mL and had not responded to the medication therapy, were included. The prostate size, prostate-specific antigen (PSA), enucleation and morcellation times, postoperative International Prostate Symptom Score (IPSS), and International Index of Erectile Function-5 (IEFF-5) records at 1, 3, 6, and 12 months were among the information gathered.

Results: The average age of the 80 patients who received ThuLEP was 66.7 ±6.4 years, with a mean prostate volume of 112.65 ±19.3 mL. The mean duration for enucleation was 71 ±11 min. At the initial follow-up after one month, the mean IPSS was 8.012 ±1.78 mL and the mean Qmax enhancement was 30.16 ±4 mL s-1. In contrast to baseline, our findings demonstrated a substantial improvement in postoperative urgency and urgency urinary incontinence (UUI) (p = 0.005) but no meaningful variation in IIEF-5 score at the 12-month follow-up.

Conclusions: Low-power ThuLEP is worthwhile for therapeutic use because it effectively treats patients with large prostates with satisfactory urinary and sexual effects.Clinical trials .gov ID: NCT05494944.

本研究的目的是评估低功率铥(30w)的有效性和消除手术囊水平腺瘤所需的时间,以及其对术后泌尿和性功能的影响。材料和方法:纳入2019年12月至2022年3月期间患有ThuLEP且前列腺大小>80 mL且对药物治疗无反应的症状性良性前列腺增生(BPH)患者。收集1、3、6、12个月的前列腺大小、前列腺特异性抗原(PSA)、去核和分块次数、术后国际前列腺症状评分(IPSS)和国际勃起功能指数-5 (ief -5)记录。结果:80例患者平均年龄66.7±6.4岁,平均前列腺体积112.65±19.3 mL,平均去核时间71±11 min, 1个月后首次随访,平均IPSS为8.012±1.78 mL,平均Qmax增强为30.16±4 mL s-1。与基线相比,我们的研究结果显示术后尿急和尿急尿失禁(UUI)有显著改善(p = 0.005),但在12个月的随访中IIEF-5评分没有显著变化。结论:小倍率ThuLEP能有效治疗大前列腺患者,且效果满意。临床试验。gov ID: NCT05494944。
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引用次数: 0
Spermatic vein thrombosis as a rare cause of testicular pain - review of the literature. 精索静脉血栓形成是睾丸疼痛的一种罕见病因——文献综述。
Pub Date : 2023-01-01 Epub Date: 2023-07-14 DOI: 10.5173/ceju.2023.13
Krzysztof Kowalik, Paweł Narożnicki, Andrzej Modrzejewski

Introduction: The authors in this paper discuss a rare disease entity that can cause testicular pain and mimic varicocele.

Material and methods: Citing data from a review of the world literature, spermatic cord thrombosis is most often misdiagnosed as an incarcerated inguinal hernia. Patients usually complain of pain and swelling of the testicle, pain in the inguinal region, and sometimes a palpable mass in the inguinal region.

Results: Ultrasonography with colour Doppler usually establishes the correct diagnosis. Currently, there are no official recommendations for the treatment of this disease.There are reports of conservative treatment of spermatic cord thrombosis in the world literature. However, it seems that the gold standard of management remains surgical exploration, which allows us to unequivocally establish the correct diagnosis. In cases of co-morbid thrombosis with spermatic cord varicocelectomy is recommended.

Conclusions: Due to the rarity of this disease, the topic of this article was undertaken. The paper reviews the world literature relating to the diagnosis and treatment of this disease entity. Our own algorithm for the management of spermatic cord thrombosis is proposed.

简介:作者在本文中讨论了一种罕见的疾病实体,可以引起睾丸疼痛和模拟精索静脉曲张。材料和方法:引用世界文献回顾的数据,精索血栓形成最常被误诊为嵌顿性腹股沟疝。患者通常主诉睾丸疼痛和肿胀,腹股沟区疼痛,有时腹股沟区可触及肿块。结果:彩色多普勒超声检查能正确诊断本病。目前,对于这种疾病的治疗还没有官方的建议。世界文献中有保守治疗精索血栓的报道。然而,治疗的黄金标准似乎仍然是手术探查,这使我们能够明确地建立正确的诊断。在与精索合并血栓形成的病例中,建议行精索静脉曲张切除术。结论:由于本病的罕见性,本文的主题被承担。本文对国内外有关该病诊断和治疗的文献作一综述。我们自己的算法管理精索血栓提出。
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引用次数: 0
Correlation of Doppler ultrasound resistive index in the prostatic gland with severity of male lower urinary tract symptoms, prostate volume, and concomitant diabetes mellitus. 前列腺多普勒超声阻力指数与男性下尿路症状严重程度、前列腺体积及合并糖尿病的相关性
Pub Date : 2023-01-01 Epub Date: 2023-07-13 DOI: 10.5173/ceju.2023.47
Tolulope Adebayo Okedere, Christianah Mopelola Asaleye, Oluwagbemiga Oluwole Ayoola, Babatope Ayodeji Kolawole, Abdulkadir Ayo Salako, Bukunmi Michael Idowu, Stephen Olaoluwa Onigbinde, Babatunde Opeyemi Oguntade

Introduction: Benign prostatic enlargement (BPE) and type 2 diabetes mellitus (T2DM) are common in elderly men. This study aimed to correlate the Doppler resistive indices of prostatic arteries with the severity of lower urinary tract symptoms (LUTS) and prostate volume in men with concomitant BPE and T2DM.

Material and methods: Fifty men with T2DM and BPE (BPE-DM) as cases and 50 age-matched men with BPE but no T2DM (BPE-ND) as controls were enrolled. B-mode and power Doppler ultrasonography of the prostate gland were done for both groups.

Results: The mean total prostatic volume of the BPE-DM was 79.18 ±8.9 ml, while that of BPE-ND was 60.73 ±10.6 ml (p <0.0001). The mean prostatic resistive index (PRI) was significantly higher among BPE-DM than BPE-ND (0.74 ±0.02 vs 0.68 ±0.09 for right capsular artery; 0.77 ±0.04 vs 0.71 ±0.02 for left capsular artery; and 0.76 ±0.04 vs 0.70 ±0.02 for the urethral artery). BPE-DM with higher glycated haemoglobin, fasting plasma glucose, and longer duration of T2DM experienced more severe lower urinary tract symptoms and had higher PRI.

Conclusions: In conclusion, the BPE-DM group presented larger prostate glands and more bothersome LUTS, which correlated with higher PRI. Strict glycaemic control is necessary in men with co-existing BPE and T2DM.

良性前列腺肥大(BPE)和2型糖尿病(T2DM)在老年男性中很常见。本研究旨在探讨前列腺动脉多普勒阻力指数与BPE合并T2DM患者下尿路症状(LUTS)严重程度和前列腺体积的相关性。材料和方法:入选50例伴有T2DM和BPE的男性(BPE- dm)和50例年龄匹配的伴有BPE但无T2DM的男性(BPE- nd)作为对照。两组均行前列腺b超和功率多普勒超声检查。结果:BPE- dm患者平均前列腺总体积为79.18±8.9 ml, BPE- nd患者平均前列腺总体积为60.73±10.6 ml (p)。结论:BPE- dm组前列腺体积较大,LUTS更麻烦,且PRI较高,BPE合并T2DM患者需严格控制血糖。
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引用次数: 0
Choosing a path for CEJU 为CEJU选择路径
Pub Date : 2023-01-01 DOI: 10.5173/ceju.2023.01ev
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引用次数: 0
Location of ureteral access sheath in the ureter. Does it affect the fluid flow in different calyces? 输尿管通路鞘在输尿管的位置。它会影响不同花萼中的液体流动吗?
Pub Date : 2023-01-01 Epub Date: 2023-08-26 DOI: 10.5173/ceju.2023.03
Gabriel Faria-Costa, Arman Tsaturyan, Angelis Peteinaris, Konstantinos Pagonis, Solon Faitatziadis, Kristiana Gkeka, Anastasios Natsos, Irini Anaplioti, Mohammed Obaidat, Theofanis Vrettos, Evangelos Liatsikos, Panagiotis Kallidonis

Introduction: The aim of this study was to evaluate outflow variation in different locations of the pyelocaliceal system with the use of different ureteral access sheath (UAS) sizes and different UAS positioning.

Material and methods: The experimental setup included an anaesthetised porcine model, a 7.5-Fr ureteroscope with a 200-μm laser fibre inserted in the working channel, a hand-held pumping irrigating system, and UAS of different sizes, namely: 9.5/11.5 Fr, 12/14 Fr, and 14/16 Fr. Each UAS was placed just below the ureteropelvic junction (UPJ) or in the mid-ureter. The ureteroscope was placed in the renal pelvis, upper and lower calyces, and outflow measurements were obtained with 3-second interval pumping for one minute in every experimental setup.

Results: The UAS positioning in the mid-ureter was associated with significantly higher outflow rates in the lower calyx (p = 0.041). While the UAS was below the UPJ, we observed a trend of lower outflow rate in the lower calyx, which was completely inverted when the UAS was in the mid-ureter. Increasing the UAS size from 9.5/11.5 Fr to 12/14 Fr led to a significant increase in outflow in the renal pelvis and upper calyx (p = 0.007), but not in the lower calyx. A further increase to 14/16 Fr did not produce increased flow.

Conclusions: Different locations of the pyelocaliceal system have different fluid mechanics during fURS. In the renal pelvis and upper calyx increasing the diameter of the UAS improved the outflow, whereas in the lower calyx the position of the UAS seems to be the most relevant factor. These variables should be considered when performing fURS, especially with high-power laser lithotripsy.

摘要:本研究的目的是评估不同输尿管导管鞘(UAS)尺寸和不同输尿管导管鞘(UAS)位置在肾盂局部系统不同位置的流出量变化。材料和方法:实验装置包括麻醉猪模型,工作通道内插入200 μm激光光纤的7.5 Fr输尿管镜,手摇泵灌系统和不同尺寸的UAS,即9.5/11.5 Fr, 12/14 Fr和14/16 Fr。每个UAS放置在输尿管盆腔连接(UPJ)下方或输尿管中部。输尿管镜放置于肾盂、上肾盏和下肾盏,每次实验间隔3秒泵送1分钟,测量流出量。结果:UAS位于输尿管中端与下肾盏流出率显著升高相关(p = 0.041)。当UAS位于UPJ下方时,我们观察到下肾萼流出率较低的趋势,而当UAS位于输尿管中段时,这一趋势完全逆转。将UAS的大小从9.5/11.5 Fr增加到12/14 Fr,导致肾盂和上肾盏的流出量显著增加(p = 0.007),但下肾盏的流出量没有增加。进一步增加到14/16 Fr并没有增加流量。结论:肾盂局部系统不同部位在fURS时具有不同的流体力学。在肾盂和上肾盏中,增加UAS的直径可以改善流出,而在下肾盏中,UAS的位置似乎是最相关的因素。在进行fURS时应考虑这些变量,特别是在高功率激光碎石术中。
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引用次数: 0
Mild elevation of liver function tests associated with renal cell carcinoma in a multimorbid older patient - a case of Stauffer's syndrome. 多病老年患者肾细胞癌相关肝功能检查轻度升高-斯托弗综合征1例
Pub Date : 2023-01-01 Epub Date: 2023-07-26 DOI: 10.5173/ceju.2023.98
Monika Ryś, Karolina Piotrowicz, Marcin Chłosta, Mateusz Ostachowski, Barbara Gryglewska, Piotr Chłosta, Jerzy Gąsowski

We describe a case of a 74-year-old patient with recurrent fever of up-to 38.5°C, nocturnal sweating, weight loss of 4 kg, non-characteristic pain, and elevation of liver function tests (LFTs), who was diagnosed with Stauffer's syndrome. The patient successfully underwent laparoscopic heminephrectomy. The histology was clear-cell carcinoma of the right kidney (cT1a). The abnormalities in laboratory tests, such as Erythrocyte Sedimentation Rate, C-reactive protein, LFTs, α2-globulin, and most clinical symptoms abated 2 weeks post-surgery. We hypothesize that elevated LFTs in renal cell carcinoma patients could help deciding in favour of surgery in cases where the initial decision would be watchful waiting.

我们描述了一例74岁的患者,反复发烧高达38.5°C,夜间出汗,体重减轻4kg,非特征性疼痛,肝功能检查(LFTs)升高,被诊断为斯托弗综合征。该患者成功地接受了腹腔镜半肾切除术。病理表现为右肾透明细胞癌(cT1a)。术后2周,血沉、c反应蛋白、LFTs、α2-球蛋白等实验室检查异常及大部分临床症状均有所缓解。我们假设,肾细胞癌患者的LFTs升高有助于在最初的决定需要观察等待的情况下决定是否进行手术。
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引用次数: 0
A new era and future of education: the impact of pandemic on online learning - a study from the European School of Urology. 教育的新时代和未来:流行病对在线学习的影响——欧洲泌尿学院的一项研究。
Pub Date : 2023-01-01 Epub Date: 2023-06-26 DOI: 10.5173/ceju.2023.059
Juan Gómez Rivas, Inés Rivero Belenchón, Nan Li, Bhaskar Somani, Eva Andres Esteban, Giovanni Cacciamani, Enrico Checcucci, Stefano Puliatti, Mark Taratkin, Karl-Friedrich Kowalewski, Severin Rodler, Alessandro Veccia, Joan Palou, Evangelos Liatsikos

Introduction: In contemporary times, the online learning process has become indispensable for healthcare education. In this direction, the European School of Urology (ESU) has taken the challenge to implement new technologies to bring down knowledge barriers. Web-based seminars (webinars) are one of the tools that help us move towards such inclusivity, and in front-facing COVID-19 pandemic, when face-to-face meetings were forbidden.

Material and methods: Data from ESU webinars was collected from 2016 to 2022. We described the trends through years of: a) number of webinars per year; b) number of oncological versus non-oncological webinars per year; c) number of registrations per year; d) attendance rate; e) YouTube visualisations. We also analysed audience demographics and COVID-19 impact.

Results: We found a 60% increase in webinars launched per year with a trend towards more non-oncological webinars. A 94% rise in the number of registrations and an 85% increase in the attendance ratio from 2016 to 2022 was observed. The mean YouTube visualisations per webinar decreased over 200%. Among registrations, we had a 3:1 male: female ratio, 53% were older than 40, and a 51% were of European precedence. COVID-19 positively impacted webinars with a remarkable increase on the amount of webinars launched, number of registrations and attendance ratio.

Conclusions: Webinars are a powerful tool to spread healthcare knowledge, bridging the gap in medical educational access. COVID-19 was a determinant that reinforced its implantation, but our data show that this new learning tool had a positive uptake, and has come to stay.

导读:在当今时代,在线学习过程已经成为医疗保健教育不可或缺的一部分。在这个方向上,欧洲泌尿外科学院(ESU)已经接受了实施新技术的挑战,以消除知识障碍。在面对面会议被禁止的情况下,网络研讨会是帮助我们实现这种包容性的工具之一。材料和方法:收集2016 - 2022年ESU网络研讨会的数据。我们描述了多年来的趋势:a)每年的网络研讨会数量;B)每年肿瘤学与非肿瘤学网络研讨会的数量;C)每年的注册数量;D)出勤率;e) YouTube可视化。我们还分析了受众人口统计和COVID-19的影响。结果:我们发现每年举办的网络研讨会增加了60%,并且有越来越多的非肿瘤学网络研讨会的趋势。从2016年到2022年,注册人数增加了94%,出勤率增加了85%。每个网络研讨会的YouTube可视化平均减少了200%以上。在注册者中,我们的男女比例为3:1,53%的人年龄在40岁以上,51%的人有欧洲先例。新冠肺炎疫情对网络研讨会产生了积极影响,网络研讨会的启动数量、报名人数和出席率均显著增加。结论:网络研讨会是传播医疗保健知识的有力工具,可弥合医学教育机会的差距。COVID-19是加强其植入的一个决定因素,但我们的数据显示,这一新的学习工具得到了积极的吸收,并得到了保留。
{"title":"A new era and future of education: the impact of pandemic on online learning - a study from the European School of Urology.","authors":"Juan Gómez Rivas, Inés Rivero Belenchón, Nan Li, Bhaskar Somani, Eva Andres Esteban, Giovanni Cacciamani, Enrico Checcucci, Stefano Puliatti, Mark Taratkin, Karl-Friedrich Kowalewski, Severin Rodler, Alessandro Veccia, Joan Palou, Evangelos Liatsikos","doi":"10.5173/ceju.2023.059","DOIUrl":"10.5173/ceju.2023.059","url":null,"abstract":"<p><strong>Introduction: </strong>In contemporary times, the online learning process has become indispensable for healthcare education. In this direction, the European School of Urology (ESU) has taken the challenge to implement new technologies to bring down knowledge barriers. Web-based seminars (webinars) are one of the tools that help us move towards such inclusivity, and in front-facing COVID-19 pandemic, when face-to-face meetings were forbidden.</p><p><strong>Material and methods: </strong>Data from ESU webinars was collected from 2016 to 2022. We described the trends through years of: a) number of webinars per year; b) number of oncological versus non-oncological webinars per year; c) number of registrations per year; d) attendance rate; e) YouTube visualisations. We also analysed audience demographics and COVID-19 impact.</p><p><strong>Results: </strong>We found a 60% increase in webinars launched per year with a trend towards more non-oncological webinars. A 94% rise in the number of registrations and an 85% increase in the attendance ratio from 2016 to 2022 was observed. The mean YouTube visualisations per webinar decreased over 200%. Among registrations, we had a 3:1 male: female ratio, 53% were older than 40, and a 51% were of European precedence. COVID-19 positively impacted webinars with a remarkable increase on the amount of webinars launched, number of registrations and attendance ratio.</p><p><strong>Conclusions: </strong>Webinars are a powerful tool to spread healthcare knowledge, bridging the gap in medical educational access. COVID-19 was a determinant that reinforced its implantation, but our data show that this new learning tool had a positive uptake, and has come to stay.</p>","PeriodicalId":86295,"journal":{"name":"Urologia polska","volume":"1 1","pages":"256-262"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70778109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PSMA PET-directed surgical metastasis-directed therapy in metachronous prostate cancer. 异时性前列腺癌的PSMA pet定向手术转移定向治疗。
Pub Date : 2023-01-01 Epub Date: 2023-07-18 DOI: 10.5173/ceju.2023.69
Francesca Ambrosini, Daniel Koehler, Tarik Ghadban, Frank Jacobsen, Sophie Knipper, Gunhild von Amsberg, Thomas Steuber, Tobias Maurer
We present the case of a patient who underwent an open radical prostatectomy with pelvic lymph node dissection (Gleason 4+3, pT3a pN1 R0) in March 2017. In November 2020, prostate-specific membrane antigen (PSMA)-radioguided salvage lymph node dissection was planned due to a single left para-rectal lymph node at a [68Ga] Ga-PSMA-I&T PET. In January 2022, the [68Ga] Ga-PSMA-I&T PET showed an isolated liver lesion. Biopsy confirmed prostate adenocarcinoma. A liver segmentectomy was performed. A complete biochemical response was reported until the last follow-up (December 2022). Prostate-specific membrane antigen positron emission tomography (PSMA PET)-directed metastasis-directed therapy may be an effective treatment in selected cases, allowing a benefit in the oncological outcome.
我们报告了一例于2017年3月行开放性根治性前列腺切除术并盆腔淋巴结清扫的患者(Gleason 4+3, pT3a pN1 R0)。2020年11月,由于在[68Ga] Ga-PSMA-I&T PET上发现单个左侧直肠旁淋巴结,计划进行前列腺特异性膜抗原(PSMA)放射引导的挽救性淋巴结清扫。2022年1月,[68Ga] Ga-PSMA-I&T PET显示孤立性肝脏病变。活检证实前列腺腺癌。行肝段切除术。在最后一次随访(2022年12月)之前,报告了完整的生化反应。前列腺特异性膜抗原正电子发射断层扫描(PSMA PET)定向转移治疗可能是一种有效的治疗方法,可以在肿瘤预后方面获益。
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引用次数: 0
Could twinkling artifact be a parameter in predicting the success of shock wave lithotripsy? A prospective study. 闪光神器能否作为预测冲击波碎石术成功与否的一个参数?一项前瞻性研究。
Pub Date : 2023-01-01 Epub Date: 2023-08-26 DOI: 10.5173/ceju.2023.20
Mehmet Sevim, Okan Alkis, İbrahim Güven Kartal, Huseyin Ozgur Kazan, Oguzhan Yusuf Sonmez, Mehmet Korkmaz, Bekir Aras

Introduction: It is important to predict success before the treatment of urolithiasis. We aimed to predict the success of shock wave lithotripsy (SWL) by comparing twinkling artifact (TA) revealed through colour Doppler ultrasonography (CDUS) with stone density in non-contrast computed tomography (NCCT).

Material and methods: Eighty patients who underwent SWL between January 2021 and January 2022 were included in the study. Patients with stones of 5-20 mm in the renal pelvis and proximal ureter at NCCT were included. Patients' demographics, Hounsfield units (HU) in NCCT, and TA grades in CDUS were recorded. The stone-free rate after SWL, additional treatments, overall success rates, and the association between TA and success rates were evaluated.

Results: The mean age was 47.41 ±15.08 years. The mean BMI was 24.49 ±3.67 kg/m2. Twenty-three (28.8%) patients were TA grade 0, 33 (41.2%) patients were grade 1, and 24 (30%) were grade 2. The mean HU of TA grades 0, 1, and 2 of stones were 628 ±107, 864 ±123, and 1166 ±292, respectively. The HU increased along with the increase in the TA grade of the stone (p <0.01). The mean number of SWL sessions was 2.26 ±0.75 in patients with TA grade 0, and 2.92 ±0.40 in patients with TA grade 2. The mean number of SWL sessions increased along with the increase in TA grade (p <0.01). The stone-free rate decreased as the TA grade increased. Stone diameter and TA were the only predictors of SWL success.

Conclusions: We think that TA may be useful in predicting SWL success.

导读:在尿石症治疗前预测成功是很重要的。我们的目的是通过比较彩色多普勒超声(CDUS)显示的闪烁伪影(TA)与非对比计算机断层扫描(NCCT)显示的结石密度,来预测冲击波碎石(SWL)的成功。材料和方法:在2021年1月至2022年1月期间接受SWL的80例患者纳入研究。包括肾盂和输尿管近端结石5- 20mm的患者。记录患者的人口统计学、NCCT的Hounsfield单位(HU)和CDUS的TA分级。评估SWL后的无结石率、附加治疗、总体成功率以及TA与成功率之间的关系。结果:患者平均年龄47.41±15.08岁。平均BMI为24.49±3.67 kg/m2。TA 0级23例(28.8%),1级33例(41.2%),2级24例(30%)。TA 0、1、2级结石的平均HU分别为628±107、864±123、1166±292。HU随结石TA分级的增加而增加(p)结论:我们认为TA可能有助于预测SWL的成功。
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引用次数: 0
Efficacy of combined organ-sparing management of invasive upper tract urinary cancer 保留器官联合治疗侵袭性上尿路癌的疗效观察
Pub Date : 2023-01-01 DOI: 10.5173/ceju.2023.172
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引用次数: 0
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