Daclatasvir/Sofosbuvir治疗1例9岁男童急性丙型肝炎病毒感染

IF 0.3 Q4 PEDIATRICS Journal of Child Science Pub Date : 2022-01-01 DOI:10.1055/s-0042-1751269
P. Rahmani, F. Farahmand, Ghobad Heidari
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引用次数: 0

摘要

本研究包括一个9岁男孩的病例报告,他来到我们的中心,黄疸,肝酶升高,可触及的肝脏。患者接受熊去氧胆酸治疗,但症状未见改善。逆转录聚合酶链反应和肝活检均为丙型肝炎病毒阳性。daclatasvir/sofosbuvir治疗3个月。Daclatasvir/sofosbuvir可能对儿童肝炎治疗有效,没有缓解和最小副作用的报道。
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Acute Hepatitis C Virus Infection Treated with Daclatasvir/Sofosbuvir in a 9-Year-Old Boy
The present study includes a case report of a 9-year-old boy who came to our center with jaundice, elevated liver enzymes, and palpable liver. He was treated with ursodeoxycholic acid, but no improvement in symptoms was seen. Reverse transcription polymerase chain reaction and liver biopsy were positive for hepatitis C virus. He was treated with daclatasvir/sofosbuvir for 3 months. Daclatasvir/sofosbuvir might be effective against the treatment of hepatitis in children, with no report of remission and minimal side effects.
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19
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