生物相容性形态学平均试验测定乳胶手套中的蛋白质浓度

C. Toa, K. S. Sim, Y. Chan
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引用次数: 0

摘要

乳胶手套被视为医疗保健领域不可或缺的物品,因为它为医护人员和患者提供了卓越的保护,使其免受有害物质的侵害。然而,高蛋白浓度的乳胶手套很有可能引发乳胶过敏,在最坏的情况下,乳胶过敏可能导致危及生命的情况。为了最大限度地减少过敏反应的发生,提出了用于蛋白质检测的计算机生物相容性形态学平均值(BMM)测试。该测试最初通过化学过程来确定手套样品中的蛋白质。之后,样本被电子转换为数字图像。最后,对图像进行彩色图像处理以计算色差值。然后将这些值绘制在标准曲线上。标准曲线的高相关系数(R2>0.97)给出了更好的精度。所提出的方法只需要大约40分钟就可以完成测试,而现有的方法至少需要6个小时。
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Protein Concentration Determination in Latex Glove Using Biocompatibility Morphological Mean Test
Latex gloves are seen as an indispensable item in the healthcare field because it offers superior protection for both the medical staff and patient against harmful substances. However, latex gloves with high protein concentration have a high possibility to induce latex allergy which in the worst case can lead to a life-threatening condition. To minimize the occurrence of an allergy reaction, the computerized Biocompatibility Morphological Mean (BMM) test for protein detection is proposed. This test initially goes through the chemical process to determine the protein that resides in the glove sample. After that, the sample is electronically converted into a digital image. Finally, the image undergoes color image processing for calculating the color difference values. These values are then plotted on a standard curve. A high correlation coefficient (R2>0.97) of the standard curve gives better accuracies. The proposed method only takes about 40 minutes to complete the test, while existing methods need at least 6 hours.
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