Tao Zhang, Liang Yu, Shunli Fan, Fei Pan, Dong Zhang, Q. He
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Systematic review of enhanced recovery after surgery in perioperative management of pancreaticoduodenectomy: a meta-analysis of randomized controlled trials and non-randomized controlled trials
Objective
To systematically review the safety and efficacy of enhanced recovery after surgery (ERAS) in perioperative management of pancreaticoduodenectomy.
Methods
A search was performed in databases (including PubMed, EMASE, Cochrane library, Sinomed, Wangfang, VIP, and CNKI) for randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) up to September 2016 on use of ERAS in patients undergoing pancreaticoduodenectomy. After quality evaluation and data extraction, meta-analysis was performed using RevMan 5.3.
Results
Four RCTs and Twelve NRCTs involving a total of 2 828 patients were included. 1 401 patients were in the ERAS group, and 1 427 in the control group. Meta-analysis results showed that compared with the control group, the ERAS group had shorter length of hospital stay (SMD=-0.36, 95% CI=-0.44--0.28, P 0.05).
Conclusion
It is reasonably safe and efficacious to adopt ERAS in periopetative management of patients undergoing pancreaticoduodenectomy.
Key words:
Enhanced recovery after surgery; Pancreaticoduodenectomy; Perioperative; Meta-analysis
期刊介绍：
The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch.
The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.
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