紫薇种子生物活性新探索

Mona M Okba, G. Jaleel, M. Yousif, K. Deeb, F. Soliman
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引用次数: 2

摘要

摘要在发展中国家贫困加剧的全球背景下,天然产品在开发新药方面很重要。Vicia ervilia L.Willd。,与蚕豆科的几种种子不同,迄今为止还没有供人类食用。我们的目标是发现这种种子的任何可能的药用用途。分别采用热板法、卡拉胶诱导的大鼠足水肿法、乙醇诱导的溃疡模型法和四氧嘧啶诱导的糖尿病法评价其镇痛、抗炎、抗溃疡和抗高血糖活性。使用甲基噻唑四氮唑测定法评估抗病毒活性。ervilia种子乙醇提取物(70%)具有显著的抗炎、镇痛、抗溃疡、抗高血糖和抗病毒活性。它是发展中国家治疗几种疾病的绝佳选择,因为它的资源多样,易于获得,负担得起,而且最新证明它具有广泛的生物活性。
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Vicia ervilia L. seeds newly explored biological activities
Abstract Within the global context of increasing poverty in the developing countries, natural products are important in devising new drugs. Vicia ervilia L. Willd., unlike several fabaceae seeds, is not used for human consumption till now. We aim to discover any possible medicinal use of the seed. Analgesic, anti-inflammatory, antiulcerogenic and antihyperglycemic activities were evaluated using hot plate, carrageenan-induced rat paw edema, ethanol-induced ulcer model and alloxan-induced diabetes methods, respectively. Antiviral activity was evaluated using Methylthiazol Tetrazolium assay. V. ervilia seeds ethanol (70%) extract had significant anti-inflammatory, analgesic, antiulcerogenic, antihyperglycemic and antiviral activities. It is of excellent choice for treatment of several illnesses in developing countries due to its diverse resource, easy accessibility, affordability and its newly proved significant wide range of biological activities.
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Cogent Biology
Cogent Biology MULTIDISCIPLINARY SCIENCES-
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