急诊科受污染血培养的危险因素:一项前瞻性队列研究

IF 3 4区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES Microbial Risk Analysis Pub Date : 2023-08-01 DOI:10.1016/j.mran.2023.100264

Koshi Ota , Yuriko Takeda , Daisuke Nishioka , Masahiro Oka , Emi Hamada , Kanna Ota , Yuriko Shibata , Kazuma Yamakawa , Akira Takasu

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引用次数: 0

摘要

背景:我们的目的是确定与急诊科(ED)污染血培养率相关的危险因素。方法在大学附属医院急诊科进行为期26个月的1098例≥20岁连续患者的单中心队列研究。结果共分析了2096对血培养。在2096对血培养物中鉴定出172例(8.2%)存在潜在污染。多因素分析显示，使用聚维酮碘(PVI)消毒穿刺部位时，污染发生率高于酒精/葡萄糖酸氯己定(校正优势比为7.13;95%置信区间[CI]， 4.8-10.7;P & lt;0.001)。股静脉和中心静脉导管比外周静脉导管更容易受到污染。第一年或第二年住院医生采集的血液没有显示出受污染血液培养物的增加。结论血培养污染率与PVI及特定部位有显著相关性，与居民采血量无显著相关性。

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Risk factors for contaminated blood cultures in the emergency department: A prospective cohort study

Background

We aimed to determine risk factors associated with rates of contaminated blood cultures in the emergency department (ED).

Methods

This single-center, cohort study of 1098 consecutive patients ≥ 20 years of age was performed in the ED of university hospital over a 26-month period.

Results

We analyzed 2096 pairs of blood cultures. Potential contamination was identified in 172 (8.2%) of the 2096 pairs of blood cultures. Multivariate analysis revealed more frequent contamination when puncture sites were disinfected with povidone-iodine (PVI) than with alcohol/chlorhexidine gluconate (adjusted odds ratio, 7.13; 95% confidence interval [CI], 4.8–10.7; P < 0.001). Femoral and central venous catheters showed more frequent contamination than peripheral venous sites. Blood collection by first- or second-year residents did not show an increase in contaminated blood cultures.

Conclusions

Rates of contaminated blood cultures were significantly associated with PVI and specific sites, but were not significantly associated with blood collection by residents.

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来源期刊

Microbial Risk Analysis Medicine-Microbiology (medical)

CiteScore

5.70

自引率

7.10%

发文量

审稿时长

52 days

期刊介绍： The journal Microbial Risk Analysis accepts articles dealing with the study of risk analysis applied to microbial hazards. Manuscripts should at least cover any of the components of risk assessment (risk characterization, exposure assessment, etc.), risk management and/or risk communication in any microbiology field (clinical, environmental, food, veterinary, etc.). This journal also accepts article dealing with predictive microbiology, quantitative microbial ecology, mathematical modeling, risk studies applied to microbial ecology, quantitative microbiology for epidemiological studies, statistical methods applied to microbiology, and laws and regulatory policies aimed at lessening the risk of microbial hazards. Work focusing on risk studies of viruses, parasites, microbial toxins, antimicrobial resistant organisms, genetically modified organisms (GMOs), and recombinant DNA products are also acceptable.