在麻醉皮肤上不断升级的热刺激的效果

D. Riccio, S. Lo Vecchio, L. Arendt-Nielsen
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引用次数: 0

摘要

瘙痒和热痛之间的关系已被广泛探索。一项70年前的研究表明,对麻醉皮肤进行热刺激后会产生矛盾的瘙痒。本研究的目的是用更现代的技术和系统的方法来重新评估这种矛盾的瘙痒效应。对19名健康受试者局部麻醉后的皮肤施加逐步升温的热刺激,在刺激过程中持续评估瘙痒和疼痛强度。正如预期的那样,局部皮内麻醉显著降低了疼痛感觉,然而,在任何刺激温度下都没有观察到矛盾的瘙痒感觉。
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The effect of escalating heat stimulation on top of anesthetized skin
The relationship between itch and heat pain has been vastly explored. A 70-year-old study, showed the development of paradoxical itch following heat stimulation of anesthetized skin. The aim of this study was to re-evaluate, with more modern technologies and systematic approaches, this paradoxical itch effect. Escalating heat stimuli were applied to the local anesthetized skin of 19 healthy subjects, itch, and pain intensities were continuously assessed during the stimulation. As expected, pain sensation was significantly reduced by local intradermal anesthesia, however, no paradoxical itch sensations were observed for any of the stimulation temperatures.
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