Effect of different grades of corpus luteum blood flow on conservative treatment in patients with unruptured tubal pregnancy

Objective To study the effect of different grades of corpus luteum blood flow on conservative treatment of unruptured tubal pregnancy. Methods One hundred and fifty-six patients who were diagnosed with unruptured tubal pregnancy in the General Hospital of Northern War Zone and accepted conservative treatment from February 2013 to February 2018 were retrospectively analyzed.The patients were divided into corpus luteum blood level 0 group(0 grade group, 36 cases), corpus luteum blood level 1 group(1 grade group, 41 cases), corpus luteum blood level 2 group(2 grade group, 45 cases), corpus luteum blood level 3 group(3 grade group, 34 cases)according to the corpus luteum blood flow classification in pregnancy.The levels of blood β-HCG, the packet reducing and the curative effect were compared among the four groups. Results The time ofβ-HCG decreased to normal after treatment in 0~3 grade group was (14.4±2.7) d, (16.2±3.9) d, (23.3±4.8) d, (27.0±4.6) d respectively, there was significant difference among the four groups (F=5.338, P=0.039). The time of mass disappeared completely after treatment in 0-3 grade group was (13.2±2.2)d, (15.9±3.0)d, (21.8±2.9)d, (24.1±3.4)d respectively, there was significant difference among the four groups (F=4.229, P=0.043). The curative rate in 0-3 grade group was 91.7%(33/36), 87.8%(36/41), 82.2%(37/45), 73.5%(25/34) respectively, there was significant difference among the four groups(χ2=4.586, P=0.041). There was no significant difference in incidence of adverse reactions among the four groups (P>0.05). Conclusion The different classification of corpus luteum blood flow in pregnancy of unruptured tubal pregnancy have significant influence on the conservative treatment effect.The higher the blood flow classification, the longer treatment time and the worse the curative effect. Key words: Tubal pregnancy; Corpus luteum of pregnancy; Blood flow classification; Conservative treatment