阿尔茨海默病的精准健康:基于风险评估的策略

IF 0.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Precision Medical Sciences Pub Date : 2021-03-01 DOI:10.1002/prm2.12036
J. Azar, M. Salama, Saravanabau Chidambaram, Buthaina Al-Balushi, M. Essa, M. Qoronfleh
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引用次数: 1

摘要

阿尔茨海默病(AD)是一种长期影响个体认知功能的慢性神经退行性疾病。AD的治疗和预防一直备受追捧;然而,目前还没有成功的策略,因为认知障碍患者通常在疾病晚期出现在诊所。该病是进行性的,其发病机制是多因素的。精准医学(PM)是医学的新时代,包括处理疾病的整体方法。通过科学创新,PM提高了我们的疾病知识,改变了诊断和治疗方法,从而实现了更精确、预测性、预防性和个性化的患者护理。AD中的PM侧重于根据个体发展疾病的风险因素对其进行分层,并应用预防策略和个性化治疗方法以获得更好的结果。在这次小型审查中,我们重点关注了一些可修改和不可修改的风险因素,并提出了建议,供未来考虑实施。
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Precision health in Alzheimer disease: Risk assessment‐based strategies
Alzheimer disease (AD) is a chronic neurodegenerative condition that affects an individual's cognitive function over an extended period. Treatment and prevention for AD have long been sought after; however, no strategy has yet been successful, as individuals with cognitive impairment usually present to the clinic when they have reached an advanced stage of the disease. The disease is progressive and multifactorial in its pathogenesis. Precision medicine (PM) is the new era of medicine comprising a holistic approach in dealing with diseases. With scientific innovations, PM has improved our disease knowledge, altered diagnoses and therapy approaches resulting in a more precise, predictive, preventative and personalized patient care. PM in AD focuses, among other things, on stratifying individuals according to their risk factors of developing the disease and applying preventative strategies and personalized treatment approaches for a better outcome. In this mini‐review, we have focused on a few modifiable and non‐modifiable risk factors and presented recommendations for future consideration to implement.
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来源期刊
Precision Medical Sciences
Precision Medical Sciences MEDICINE, RESEARCH & EXPERIMENTAL-
自引率
0.00%
发文量
33
审稿时长
15 weeks
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