面颈部放线菌病的临床病理谱

IF 2.1 Q2 MEDICINE, GENERAL & INTERNAL BioMedicine-Taiwan Pub Date : 2023-07-01 DOI:10.51248/.v43i3.2506
C. G. V., Vatsala K. B., Soumya Gupta, M. Mohan, Deepa Adiga, Cheryl Sarah Philipose, Ranjitha Rao
{"title":"面颈部放线菌病的临床病理谱","authors":"C. G. V., Vatsala K. B., Soumya Gupta, M. Mohan, Deepa Adiga, Cheryl Sarah Philipose, Ranjitha Rao","doi":"10.51248/.v43i3.2506","DOIUrl":null,"url":null,"abstract":"Introduction and Aim: Cervicofacial actinomycosis is a rare chronic granulomatous disease caused by Actinomyces and is the commonest subtype of actinomycosis. Due to the similarities in clinical presentation, cervicofacial actinomycosis is almost always suspected as malignancy or tuberculosis. Histopathological evaluation is crucial in diagnosis and management of these cases. The aim of the study was to evaluate the clinicopathological features of cervicofacial actinomycosis in the biopsy specimens.\n \nMethodology: This is a retrospective cross sectional observational study of 17 years duration. All cases of cervicofacial actinomycosis diagnosed on biopsy specimens were analyzed. Clinical presentations and histomorphological features were evaluated on hematoxylin and eosin-stained slides with confirmation of organism on special stains.\n \nResults:  Out of 36 diagnosed cases of actinomycosis during the study period, we evaluated 16 cases (44.4%) of cervicofacial actinomycosis. Mean age of presentation was 38 years. Male to female ratio was 1:0.9. The anatomical sites of eight (50%) were in the oral cavity, six (37.5%) on the face and two (12.5%) in the neck. Two cases (12.5%) had sinuses discharging sulphur granules. Six cases (37.5%) were clinically suspected as malignant and among them two cases (12.5%) also had differential diagnosis of tuberculosis. All cases on histomorphology showed sulphur granules consisting of basophilic filamentous bacterial colonies with Splendore Hoeppli phenomenon and mixed inflammation. On special stains, the bacterial colonies were Gram, PAS and GMS stain positive, and acid fast negative.\n \nConclusion: Cervicofacial actinomycosis are uncommon. Their presentation can mimic carcinoma or tuberculosis. Consistent histomorphological features can direct towards identification of organisms by special stains for confirmation of diagnosis.","PeriodicalId":51650,"journal":{"name":"BioMedicine-Taiwan","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinicopathological spectrum of cervicofacial actinomycosis\",\"authors\":\"C. G. V., Vatsala K. B., Soumya Gupta, M. Mohan, Deepa Adiga, Cheryl Sarah Philipose, Ranjitha Rao\",\"doi\":\"10.51248/.v43i3.2506\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction and Aim: Cervicofacial actinomycosis is a rare chronic granulomatous disease caused by Actinomyces and is the commonest subtype of actinomycosis. Due to the similarities in clinical presentation, cervicofacial actinomycosis is almost always suspected as malignancy or tuberculosis. Histopathological evaluation is crucial in diagnosis and management of these cases. The aim of the study was to evaluate the clinicopathological features of cervicofacial actinomycosis in the biopsy specimens.\\n \\nMethodology: This is a retrospective cross sectional observational study of 17 years duration. All cases of cervicofacial actinomycosis diagnosed on biopsy specimens were analyzed. Clinical presentations and histomorphological features were evaluated on hematoxylin and eosin-stained slides with confirmation of organism on special stains.\\n \\nResults:  Out of 36 diagnosed cases of actinomycosis during the study period, we evaluated 16 cases (44.4%) of cervicofacial actinomycosis. Mean age of presentation was 38 years. Male to female ratio was 1:0.9. The anatomical sites of eight (50%) were in the oral cavity, six (37.5%) on the face and two (12.5%) in the neck. Two cases (12.5%) had sinuses discharging sulphur granules. Six cases (37.5%) were clinically suspected as malignant and among them two cases (12.5%) also had differential diagnosis of tuberculosis. All cases on histomorphology showed sulphur granules consisting of basophilic filamentous bacterial colonies with Splendore Hoeppli phenomenon and mixed inflammation. On special stains, the bacterial colonies were Gram, PAS and GMS stain positive, and acid fast negative.\\n \\nConclusion: Cervicofacial actinomycosis are uncommon. Their presentation can mimic carcinoma or tuberculosis. Consistent histomorphological features can direct towards identification of organisms by special stains for confirmation of diagnosis.\",\"PeriodicalId\":51650,\"journal\":{\"name\":\"BioMedicine-Taiwan\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BioMedicine-Taiwan\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51248/.v43i3.2506\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BioMedicine-Taiwan","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51248/.v43i3.2506","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

摘要

引言和目的:颈面部放线菌病是一种罕见的由放线菌引起的慢性肉芽肿性疾病,是放线菌最常见的亚型。由于临床表现的相似性,面颈部放线菌病几乎总是被怀疑为恶性肿瘤或结核病。组织病理学评估对这些病例的诊断和治疗至关重要。本研究的目的是评估活组织检查标本中面颈部放线菌病的临床病理特征。方法:这是一项为期17年的回顾性横断面观察性研究。对所有经活检诊断为面颈部放线菌病的病例进行分析。在苏木精和伊红染色的载玻片上评估临床表现和组织形态学特征,并在特殊染色上确认生物体。结果:在研究期间诊断的36例放线菌病病例中,我们评估了16例(44.4%)颈面部放线菌症。平均发病年龄为38岁。男女比例为1:0.9。8个(50%)的解剖部位在口腔,6个(37.5%)在面部,2个(12.5%)在颈部。2例(12.5%)鼻窦排出硫磺颗粒。6例(37.5%)临床怀疑为恶性,其中2例(12.5%)也有结核鉴别诊断。所有病例在组织形态学上均显示由嗜碱性丝状菌落组成的硫颗粒,具有Splendor-Hoeppli现象和混合炎症。在特殊染色上,菌落为革兰氏、PAS和GMS染色阳性,抗酸阴性。结论:颈面部放线菌病并不常见。它们的表现可以模仿癌症或肺结核。一致的组织形态学特征可以指导通过特殊染色来识别生物体,以确认诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Clinicopathological spectrum of cervicofacial actinomycosis
Introduction and Aim: Cervicofacial actinomycosis is a rare chronic granulomatous disease caused by Actinomyces and is the commonest subtype of actinomycosis. Due to the similarities in clinical presentation, cervicofacial actinomycosis is almost always suspected as malignancy or tuberculosis. Histopathological evaluation is crucial in diagnosis and management of these cases. The aim of the study was to evaluate the clinicopathological features of cervicofacial actinomycosis in the biopsy specimens.   Methodology: This is a retrospective cross sectional observational study of 17 years duration. All cases of cervicofacial actinomycosis diagnosed on biopsy specimens were analyzed. Clinical presentations and histomorphological features were evaluated on hematoxylin and eosin-stained slides with confirmation of organism on special stains.   Results:  Out of 36 diagnosed cases of actinomycosis during the study period, we evaluated 16 cases (44.4%) of cervicofacial actinomycosis. Mean age of presentation was 38 years. Male to female ratio was 1:0.9. The anatomical sites of eight (50%) were in the oral cavity, six (37.5%) on the face and two (12.5%) in the neck. Two cases (12.5%) had sinuses discharging sulphur granules. Six cases (37.5%) were clinically suspected as malignant and among them two cases (12.5%) also had differential diagnosis of tuberculosis. All cases on histomorphology showed sulphur granules consisting of basophilic filamentous bacterial colonies with Splendore Hoeppli phenomenon and mixed inflammation. On special stains, the bacterial colonies were Gram, PAS and GMS stain positive, and acid fast negative.   Conclusion: Cervicofacial actinomycosis are uncommon. Their presentation can mimic carcinoma or tuberculosis. Consistent histomorphological features can direct towards identification of organisms by special stains for confirmation of diagnosis.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
BioMedicine-Taiwan
BioMedicine-Taiwan MEDICINE, GENERAL & INTERNAL-
CiteScore
2.80
自引率
5.90%
发文量
21
审稿时长
24 weeks
期刊最新文献
Acute kidney injury induced lithium toxicity with concomitant neuroleptic malignant syndrome. Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury in rats. Effect of alantolactones on cardiac parameters of animals under artificially induced oxidative stress. Effect of inulin from dahlia tubers (Dahlia variabilis) extract on insulitis severity and insulin expression in diabetic rats. Loss of tyrosine 211 phosphorylation of proliferating cell nuclear antigen (PCNA) enhances postnatal mammary gland development.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1