Luca Piretti, Sonia Di Tella, Maria Rita Lo Monaco, Valentina Delle Donne, Raffaella Ida Rumiati, Maria Caterina Silveri
{"title":"帕金森病中同种特异性加工受损。","authors":"Luca Piretti, Sonia Di Tella, Maria Rita Lo Monaco, Valentina Delle Donne, Raffaella Ida Rumiati, Maria Caterina Silveri","doi":"10.1080/23279095.2022.2074299","DOIUrl":null,"url":null,"abstract":"<p><p>Experimental evidence indicates that the inferior frontal gyrus (IFG) processes emotional/affective features crucial to elaborate knowledge about social groups and that knowledge of social concepts is stored in the anterior temporal lobe (ATL).We investigated whether knowledge about social groups is impaired in Parkinson's disease (PD), in which dysfunctional connectivity between IFG and ATL has been demonstrated.PD patients (<i>N</i> = 20) and healthy controls (HC, <i>N</i> = 16) were given a lexical decision task in a semantic priming paradigm: the prime-targets included 144 words and 144 pseudowords, each preceded by three types of prime (\"animals,\" \"things,\" \"persons\"). Out of these 288 prime-targets, forty-eight were congruent (same category) and 96 incongruent (different category). Out of 48 congruent prime-targets, 24 denoted social items and 24 nonsocial items. Thus, four types of trials were obtained: congruent social; congruent nonsocial; incongruent social; incongruent nonsocial.Congruent target-words were recognized better than incongruent target-words by all groups. The semantic priming effect was preserved in PD; however, accuracy was significantly lower in PD than in HC in social items. No difference emerged between the two groups in nonsocial items.Impaired processing of words denoting social groups in PD may be due to impairment in accessing the affective/emotional features that characterize conceptual knowledge of social groups, for the functional disconnection between the IFG and the ATL.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impaired processing of conspecifics in Parkinson's disease.\",\"authors\":\"Luca Piretti, Sonia Di Tella, Maria Rita Lo Monaco, Valentina Delle Donne, Raffaella Ida Rumiati, Maria Caterina Silveri\",\"doi\":\"10.1080/23279095.2022.2074299\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Experimental evidence indicates that the inferior frontal gyrus (IFG) processes emotional/affective features crucial to elaborate knowledge about social groups and that knowledge of social concepts is stored in the anterior temporal lobe (ATL).We investigated whether knowledge about social groups is impaired in Parkinson's disease (PD), in which dysfunctional connectivity between IFG and ATL has been demonstrated.PD patients (<i>N</i> = 20) and healthy controls (HC, <i>N</i> = 16) were given a lexical decision task in a semantic priming paradigm: the prime-targets included 144 words and 144 pseudowords, each preceded by three types of prime (\\\"animals,\\\" \\\"things,\\\" \\\"persons\\\"). Out of these 288 prime-targets, forty-eight were congruent (same category) and 96 incongruent (different category). Out of 48 congruent prime-targets, 24 denoted social items and 24 nonsocial items. Thus, four types of trials were obtained: congruent social; congruent nonsocial; incongruent social; incongruent nonsocial.Congruent target-words were recognized better than incongruent target-words by all groups. The semantic priming effect was preserved in PD; however, accuracy was significantly lower in PD than in HC in social items. No difference emerged between the two groups in nonsocial items.Impaired processing of words denoting social groups in PD may be due to impairment in accessing the affective/emotional features that characterize conceptual knowledge of social groups, for the functional disconnection between the IFG and the ATL.</p>\",\"PeriodicalId\":51308,\"journal\":{\"name\":\"Applied Neuropsychology-Adult\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Neuropsychology-Adult\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1080/23279095.2022.2074299\",\"RegionNum\":4,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/6/10 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Neuropsychology-Adult","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/23279095.2022.2074299","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/6/10 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Impaired processing of conspecifics in Parkinson's disease.
Experimental evidence indicates that the inferior frontal gyrus (IFG) processes emotional/affective features crucial to elaborate knowledge about social groups and that knowledge of social concepts is stored in the anterior temporal lobe (ATL).We investigated whether knowledge about social groups is impaired in Parkinson's disease (PD), in which dysfunctional connectivity between IFG and ATL has been demonstrated.PD patients (N = 20) and healthy controls (HC, N = 16) were given a lexical decision task in a semantic priming paradigm: the prime-targets included 144 words and 144 pseudowords, each preceded by three types of prime ("animals," "things," "persons"). Out of these 288 prime-targets, forty-eight were congruent (same category) and 96 incongruent (different category). Out of 48 congruent prime-targets, 24 denoted social items and 24 nonsocial items. Thus, four types of trials were obtained: congruent social; congruent nonsocial; incongruent social; incongruent nonsocial.Congruent target-words were recognized better than incongruent target-words by all groups. The semantic priming effect was preserved in PD; however, accuracy was significantly lower in PD than in HC in social items. No difference emerged between the two groups in nonsocial items.Impaired processing of words denoting social groups in PD may be due to impairment in accessing the affective/emotional features that characterize conceptual knowledge of social groups, for the functional disconnection between the IFG and the ATL.
期刊介绍:
pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.