一种新的宫颈癌治疗方法:简要综述

Amir Sasan Mozaffari Nejad, F. Kamarehei, Amir Khodavirdipour, P. Mehrbod, M. Alikhani
{"title":"一种新的宫颈癌治疗方法:简要综述","authors":"Amir Sasan Mozaffari Nejad, F. Kamarehei, Amir Khodavirdipour, P. Mehrbod, M. Alikhani","doi":"10.2174/18749445-v16-e230405-2022-209","DOIUrl":null,"url":null,"abstract":"Cervical cancer is one of the most common cancers affecting women worldwide, and it occurs following persistent infection. Cervical cancer incidence is tightly linked to HPV infection (human papillomavirus), and particularly, type 16 and type 18 viruses cause the majority of cases. The common therapies for cervical cancer include surgery, chemotherapy, and radiation therapy, which are often invasive or unbearable treatment methods with many side effects. They just probably slow down the disease progression or alleviate any comorbid conditions, including vaginal bleeding and pain, which is called palliative care, while novel treatment approaches, especially virus-like particles and viral oncolysate, could eliminate these complications. In this review study, we have proposed a novel approach to cervical cancer therapy focused on utilizing Newcastle disease virus as viral oncolysate with a high potential of immunity induction and low side effects. Furthermore, we have attempted to shed some light on the perspectives of novel virus-based cervical cancer immunotherapy. Finally, we review the recent findings from basic and clinical studies and also discuss the usefulness and limitations of this approach, as well as the reasons why it is believed that viral oncolysate immunotherapy may be of relevance in the treatment of human cervical cancer.","PeriodicalId":38960,"journal":{"name":"Open Public Health Journal","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Novel Approach to Cervical Cancer Therapy: A Short Review\",\"authors\":\"Amir Sasan Mozaffari Nejad, F. Kamarehei, Amir Khodavirdipour, P. Mehrbod, M. Alikhani\",\"doi\":\"10.2174/18749445-v16-e230405-2022-209\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cervical cancer is one of the most common cancers affecting women worldwide, and it occurs following persistent infection. Cervical cancer incidence is tightly linked to HPV infection (human papillomavirus), and particularly, type 16 and type 18 viruses cause the majority of cases. The common therapies for cervical cancer include surgery, chemotherapy, and radiation therapy, which are often invasive or unbearable treatment methods with many side effects. They just probably slow down the disease progression or alleviate any comorbid conditions, including vaginal bleeding and pain, which is called palliative care, while novel treatment approaches, especially virus-like particles and viral oncolysate, could eliminate these complications. In this review study, we have proposed a novel approach to cervical cancer therapy focused on utilizing Newcastle disease virus as viral oncolysate with a high potential of immunity induction and low side effects. Furthermore, we have attempted to shed some light on the perspectives of novel virus-based cervical cancer immunotherapy. Finally, we review the recent findings from basic and clinical studies and also discuss the usefulness and limitations of this approach, as well as the reasons why it is believed that viral oncolysate immunotherapy may be of relevance in the treatment of human cervical cancer.\",\"PeriodicalId\":38960,\"journal\":{\"name\":\"Open Public Health Journal\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Public Health Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/18749445-v16-e230405-2022-209\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Nursing\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Public Health Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/18749445-v16-e230405-2022-209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0

摘要

癌症是世界范围内影响妇女的最常见癌症之一,它发生在持续感染之后。癌症的发病率与HPV感染(人乳头瘤病毒)密切相关,尤其是16型和18型病毒导致大多数病例。癌症的常见治疗方法包括手术、化疗和放射治疗,这些治疗方法通常是侵入性的或难以忍受的,有许多副作用。它们可能只是减缓疾病进展或缓解任何合并症,包括阴道出血和疼痛,这被称为姑息治疗,而新的治疗方法,特别是病毒样颗粒和病毒溶媒,可以消除这些并发症。在这项综述研究中,我们提出了一种新的治疗宫颈癌症的方法,重点是利用新城疫病毒作为具有高潜在免疫诱导和低副作用的病毒溶瘤物。此外,我们还试图阐明基于新型病毒的宫颈癌症免疫疗法的前景。最后,我们回顾了基础研究和临床研究的最新发现,并讨论了这种方法的有用性和局限性,以及为什么认为病毒溶瘤细胞免疫疗法可能与人类宫颈癌症的治疗相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A Novel Approach to Cervical Cancer Therapy: A Short Review
Cervical cancer is one of the most common cancers affecting women worldwide, and it occurs following persistent infection. Cervical cancer incidence is tightly linked to HPV infection (human papillomavirus), and particularly, type 16 and type 18 viruses cause the majority of cases. The common therapies for cervical cancer include surgery, chemotherapy, and radiation therapy, which are often invasive or unbearable treatment methods with many side effects. They just probably slow down the disease progression or alleviate any comorbid conditions, including vaginal bleeding and pain, which is called palliative care, while novel treatment approaches, especially virus-like particles and viral oncolysate, could eliminate these complications. In this review study, we have proposed a novel approach to cervical cancer therapy focused on utilizing Newcastle disease virus as viral oncolysate with a high potential of immunity induction and low side effects. Furthermore, we have attempted to shed some light on the perspectives of novel virus-based cervical cancer immunotherapy. Finally, we review the recent findings from basic and clinical studies and also discuss the usefulness and limitations of this approach, as well as the reasons why it is believed that viral oncolysate immunotherapy may be of relevance in the treatment of human cervical cancer.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Open Public Health Journal
Open Public Health Journal Social Sciences-Health (social science)
CiteScore
1.00
自引率
0.00%
发文量
87
期刊介绍: The Open Public Health Journal is an Open Access online journal which publishes original research articles, reviews/mini-reviews, short articles and guest edited single topic issues in the field of public health. Topics covered in this interdisciplinary journal include: public health policy and practice; theory and methods; occupational health and education; epidemiology; social medicine; health services research; ethics; environmental health; adolescent health; AIDS care; mental health care. The Open Public Health Journal, a peer reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.
期刊最新文献
Evaluating the Safety and Efficacy of Manual Lymphatic Drainage with Thai Traditional Massage on Breast Milk Volume, Breast Pain and Engorgement in Post-Cesarean Mothers of Preterm Infants: A Randomized Controlled Trial HIV/AIDS Risky Behavior Model for LGBT Youth in the Gorontalo Province Evaluation of Adverse Effects after the Second Dose of BNT162b2 Mrna Vaccination for COVID-19: A Survey-based Analysis among Italian Healthcare Workers Awareness among Healthcare Workers regarding Physical Hazards in Dental and Oral Hospitals of Semarang, Indonesia Linear and Nonlinear Associations between Meteorological Variables and the Incidence of Malaria in Zahedan District Southwest of Iran 2000-2019
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1