造疤灸足三里穴和肺俞穴对非小细胞肺癌患者中性粒细胞/淋巴细胞比值及生活质量的影响:一项随机对照试验

IF 2 4区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Traditional Chinese Medicine Pub Date : 2018-06-01 DOI:10.1016/S0254-6272(18)30636-8
Zhang Mengxue, Guan Ling, Wang Lili, Li Ying
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引用次数: 9

摘要

目的探讨热刺激生瘢痕灸足三里穴(ST 36)和肺俞穴(BL 13)对非小细胞肺癌(NSCLC)患者中性粒细胞/淋巴细胞比值(NLR)和生活质量的影响。方法70例非小细胞肺癌患者随机分为两组:A组患者每天在足三里(ST 36)和肺俞(BL 13)穴位进行造疤灸,疗程6周;B组患者不进行干预(对照组)。结果测量是NLR和欧洲癌症研究和治疗组织生活质量问卷(EORTC QLQ-C30)的分数。在基线和6周结束时评估NLR和EORTC QLQ-C30。结果5名参与者退出,最后总共有65名参与者完成了试验。A组和B组基线时的平均NLR相似。疗程结束后,A组NLR显著低于B组(P <0.001)。与B组比较,A组在整体健康状况和生活质量方面的EORTC QLQ-C30评分显著高于B组(P <0.001)和函数(P <0.05),在症状方面显著降低(P <0.05)。结论热刺激足三里穴(ST 36)和肺俞穴(BL 13)行造疤灸可有效降低NSCLC患者NLR,提高患者生活质量。
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Effect of scar-producing moxibustion at the acupoints Zusanli (ST 36) and Feishu (BL 13) on neutrophil-to-lymphocyte ratio and quality of life in patients with non-small-cell lung cancer: A randomized, controlled trial

OBJECTIVE

To evaluate the effect of heat stimulation via scar-producing moxibustion at the acupoints Zusanli (ST 36) and Feishu (BL 13) on the neutrophil-to-lymphocyte ratio (NLR) and quality of life in patients with non-small-cell lung cancer (NSCLC).

METHODS

Seventy patients with NSCLC were randomly assigned into two groups: group A received scar-producing moxibustion at the acupoints Zusanli (ST 36) and Feishu (BL 13) every day for 6 weeks, while group B received no intervention (control group). Outcome measures were the NLR and the scores from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). The NLR and the EORTC QLQ-C30 were assessed at baseline and at the end of 6 weeks.

RESULTS

Five participants dropped out, leaving a final total of 65 participants who completed the trial. Groups A and B had a similar mean NLR at baseline. After the treatment course, the NLR in group A was significantly lower than that in group B (P < 0.001). Compared with group B, the EORTC QLQ-C30 scores in group A were significantly greater in terms of global health status or quality of life (P < 0.001) and function (P < 0.05), and significantly lower in terms of symptoms (P < 0.05).

CONCLUSION

The present study suggests that performing scar-producing moxibustion by heat-stimulating the acupoints Zusanli (ST 36) and Feishu (BL 13) effectively decreases the NLR and improves the quality of life in patients with NSCLC.

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来源期刊
Journal of Traditional Chinese Medicine
Journal of Traditional Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
2.40
自引率
3.80%
发文量
32269
审稿时长
2 months
期刊介绍: Journal of Traditional Chinese Medicine(JTCM) is devoted to clinical and theortical research on the use of acupuncture and Oriental medicine. The main columns include Clinical Observations, Basic Investigations, Reviews, Questions and Answers, an Expert''s Forum, and Discussions of Clinical Cases. Its key topics include acupuncture and electro-acupuncture, herbal medicine, homeopathy, masseotherapy, mind-body therapies, palliative care, and other CAM therapies.
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