Hemodynamic changes in pediatric dental patients using 2% lignocaine, buffered lignocaine, and 4% articaine in pediatric dental procedures

Background: The purpose of this study was to compare the hemodynamic changes (blood pressure, heart rate and oxygen saturation) when using three different local anesthetic agents such 2% Lignocaine with 1:200,000 epinephrine, Buffered Lignocaine and 4% Articaine with 1:200,000 epinephrine with inferior alveolar nerve block in pediatric dental patients. Methods: A double blind crossover study was designed where in 48; 5-10 year old patients received three sections of inferior alveolar nerve block injections in three appointments which scheduled one week apart. Blood pressure, heart rate and oxygen saturation was measured before and after administration. Results: When applying three factors ANOVA, no statistically significant difference was found between Lignocaine and Buffered Lignocaine, Buffered Lignocaine and Articaine in all the three parameters(P > 0.05 ). Conclusion: This findings in hemodynamic changes from this study reveals that all the three anesthetic agents are safe in children aged 5-10 years.