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Reviewing hemangiomas and vascular malformations: An in-depth analysis 回顾血管瘤和血管畸形:深入分析
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_77_23
Zaki Sayyed, Yashmin Parveen, Antara Bhattacharyya, Ansari Mohd Arshiyan, Ahtesham Shah, Krutika Bidkar
This narrative review delves into the intricacies of hemangiomas and vascular malformations (VMs), exploring their characteristics, diagnostic approaches, and therapeutic interventions. Hemangiomas, characterized by an abnormal growth of blood vessels, and VMs, arising from developmental abnormalities in blood vessels, present multifaceted challenges in clinical practice. The review navigates through the clinical manifestations and classifications of these vascular anomalies, emphasizing the importance of accurate diagnosis based on clinical evaluation, imaging techniques, and histopathological assessment. Variations in presentation, ranging from asymptomatic lesions to severe complications impacting vital organs, underscore the necessity for comprehensive understanding and tailored management strategies. Moreover, this review examines current therapeutic modalities encompassing medical, interventional, and surgical interventions. It synthesizes the evolving landscape of treatment options and highlighting the benefits, limitations, and potential adverse effects associated with each approach. In addition, the review underscores the significance of a multidisciplinary approach, integrating expertise from dermatology, radiology, and surgery, to optimize patient care and outcomes. The challenges posed by these vascular anomalies necessitate ongoing research endeavors aimed at refining diagnostic criteria and advancing therapeutic innovations. This review amalgamates existing knowledge and providing clinicians and researchers with a comprehensive understanding of hemangiomas and VMs, thereby fostering continued exploration and innovation in this complex field.
这篇叙述性综述深入探讨了血管瘤和血管畸形(VMs)的复杂性,探讨了它们的特点、诊断方法和治疗干预措施。血管瘤的特点是血管异常生长,而血管畸形则是血管发育异常所致,它们给临床实践带来了多方面的挑战。本综述介绍了这些血管异常的临床表现和分类,强调了根据临床评估、成像技术和组织病理学评估进行准确诊断的重要性。从无症状的病变到影响重要器官的严重并发症,表现形式各不相同,这突出了全面了解和制定有针对性的管理策略的必要性。此外,这篇综述还探讨了当前的治疗模式,包括内科、介入科和外科干预。综述了不断发展的治疗方案,强调了每种方法的优点、局限性和潜在不良反应。此外,该综述还强调了多学科方法的重要性,即整合皮肤科、放射科和外科的专业知识,以优化患者护理和治疗效果。这些血管畸形所带来的挑战要求我们不断进行研究,以完善诊断标准,推动治疗创新。本综述整合了现有知识,为临床医生和研究人员提供了对血管瘤和虚拟血管的全面了解,从而促进这一复杂领域的持续探索和创新。
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引用次数: 0
Model analysis through two-dimensional evaluation of alveolar changes of untreated unilateral cleft lip and palate infants 通过对未经治疗的单侧唇腭裂婴儿牙槽变化的二维评估进行模型分析
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_25_23
Jeessica Prasad, Seema Deshmukh
The primary objective of therapeutic interventions for unilateral cleft lip and palate (UCLP) is to reestablish typical role and anatomy. The efficacy of nasoalveolar molding relies on the age at which it is initiated, thus early initiation is recommended. Evaluating the success of presurgical orthopedics involves assessing the after-treatment maxillary arch form and proportions in UCLP infants and comparing them to age-matched infants without clefts. Untreated UCLP cases exhibit various changes in the transverse and angular dimensions of the alveolar segment. Utilizing digital analysis of UCLP plaster casts through Photoshop software (version 24.0.0) can serve as an alternative method to predict changes in cleft width, arch width, and angular measurements in untreated cases.
单侧唇腭裂(UCLP)治疗干预的主要目的是重建典型的作用和解剖结构。鼻齿槽成型术的疗效取决于开始治疗的年龄,因此建议尽早开始治疗。评估手术前矫形的成功与否,包括评估 UCLP 婴儿治疗后的上颌牙弓形态和比例,并将其与无裂纹的年龄匹配婴儿进行比较。未经治疗的 UCLP 病例在牙槽段的横向和角度尺寸上表现出各种变化。通过 Photoshop 软件(24.0.0 版)对 UCLP 石膏模型进行数字分析,可作为预测未经治疗病例的裂隙宽度、牙弓宽度和角度测量变化的另一种方法。
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引用次数: 0
Magnum of magnet: Rehabilitation of surgical defect post rhinocerebral mucormycosis with hybrid prosthesis Magnum of magnet:用混合假体修复鼻脑粘液瘤病后的手术缺损
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_27_23
Rishu Koul, Sahil Verma, Dinesh Kumar, V. Legha
Midfacial defects are defined as ones limited to the middle one-third of the face in the horizontal axis which communes with intraoral maxillary defects. They affect patient’s phonation, chewing capacity, quality of life, and social and community behavior. Surgical reconstruction alone is inadequate to rehabilitate these large midfacial defects, thereby necessitating use of a maxillofacial prosthesis to restore form, function, esthetics and comfort. The present case report presents the prosthetic restoration of a surgical defect secondary to treatment of rhinocerebral mucormycosis with an extraoral (exenteration) and intraoral (Armany Class IV) defect connected with magnetic attachment.
面中部缺损是指局限于面部中间三分之一水平轴的缺损,它与上颌口内缺损共同存在。它们影响患者的发音、咀嚼能力、生活质量以及社交和社区行为。单靠手术重建不足以修复这些巨大的中面部缺损,因此需要使用颌面部假体来恢复形态、功能、美观和舒适度。本病例报告介绍了对继发于鼻脑粘液瘤病治疗的手术缺损进行修复的情况,该缺损为口外(外翻)和口内(Armany IV 级)缺损,并与磁性附着物相连。
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引用次数: 0
Evaluation and comparison of serum and salivary interleukin 9 levels among individuals with gingivitis and periodontitis and healthy controls: A cross-sectional study 牙龈炎和牙周炎患者与健康对照组血清和唾液中白细胞介素 9 水平的评估与比较:横断面研究
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_35_23
P. Abhigna, J. Prasanna, RekhaRani Koduganti
Although interleukin (IL)-9 has been understudied, some pleiotropic effects have been documented on lymphocytes and mast cells. It is a T-cell-derived cytokine. The aim of this study was to appraise the association of IL-9 in the serum and saliva of individuals with gingivitis, periodontitis, and healthy controls. It is an observational cross-sectional type. This study was conducted on 90 subjects, including both males and females, divided into three groups: gingivitis (30), Parkinson’s disease (PD) (30), and healthy (30). Clinical parameters assessed were gingival bleeding index, Russell’s periodontal index (PI), probing pocket depth, and clinical attachment level. Serum and salivary IL-9 levels were weighed by enzyme-linked immunosorbent assay. The Statistical Package for the Social Sciences version 22, (IBM, Chicago, IL, USA) was used for evaluation. The normality of the data was checked using the Shapiro–Wilks test. Analysis of variance test was used to compare the means of two or more independent (unrelated) groups, followed by Tukey’s post hoc analysis for pair-wise comparison. The analogy between IL-9 and clinical parameters was evaluated using Pearson’s correlation coefficient. The probability value was set at 0.05. Statistically significant elevation of saliva and serum IL-9 levels occurred in subjects with gingivitis, followed by PD and health. This study concluded that IL-9 may be indicated as a biomarker in the early stages of periodontal diseases.
虽然对白细胞介素(IL)-9 的研究还不够深入,但已记录了它对淋巴细胞和肥大细胞的一些多效应。它是一种源自 T 细胞的细胞因子。 本研究旨在评估牙龈炎、牙周炎患者和健康对照组血清和唾液中 IL-9 的相关性。 这是一项观察性横断面研究。 研究对象包括男性和女性,共 90 人,分为三组:牙龈炎组(30 人)、帕金森病组(30 人)和健康组(30 人)。评估的临床参数包括牙龈出血指数、罗素牙周指数(PI)、探诊袋深度和临床附着水平。血清和唾液中的 IL-9 水平通过酶联免疫吸附测定法进行称量。 使用社会科学统计软件包第 22 版(IBM,芝加哥,伊利诺斯州,美国)进行评估。使用 Shapiro-Wilks 检验检查数据的正态性。方差分析检验用于比较两个或两个以上独立(不相关)组的平均值,然后采用 Tukey 后特别分析进行配对比较。IL-9 与临床参数之间的类比采用皮尔逊相关系数进行评估。概率值设定为 0.05。 据统计,患有牙龈炎的受试者唾液和血清中的 IL-9 水平明显升高,其次是 PD 和健康状况。 这项研究认为,IL-9 可作为牙周疾病早期阶段的生物标志物。
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引用次数: 0
A comparative analysis of the antimicrobial efficacy of different concentrations of silver nanoparticles and chlorhexidine against Enterococcus faecalis - In vitro study 不同浓度纳米银和洗必泰对粪肠球菌抗菌效果的比较分析--体外研究
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_69_23
Pooja Warade, Manoj Likhitkar, Anant Kumar Heda, Deepali Birla, Thanima Chandran, N. Ingle
Root canal irrigants combat endodontic microbial flora, effectively targeting resilient microbes like Enterococcus faecalis, which persist despite treatment. Chlorhexidine (CHX), as an irrigant, boasts broad-spectrum antibacterial activity, notable substantivity in dentine, and favorable biocompatibility. In the realm of nanotechnology, the use of silver nanoparticle (AgNP) solutions appears promising, given their strong antibacterial and antimicrobial properties. The objective of the study was to compare the antimicrobial effectiveness of varying concentrations (1%, 0.75%, and 0.5%) of AgNPs and 2% CHX against E. faecalis. Four irrigant solutions, including 1%, 0.75%, and 0.5% AgNPs and 2% CHX with gentamicin as the control, will be assessed. The ATCC 29212 strain of E. faecalis will be cultivated at 37°C on brain–heart infusion Broth plates. After 48 h, the bacterial population will be quantified by counting colony-forming units on agar plates. Each irrigant will be applied to the plates, and the resulting bacterial inhibition zone will be measured. Our study demonstrates the antimicrobial effects of 1%, 0.75%, and 0.5% AgNPs and 2% CHX against E. faecalis. While 2% CHX exhibited superior activity, AgNPs at various concentrations also displayed inhibitory effects against E. faecalis. In conclusion, this study highlights the antimicrobial properties of 1%, 0.75%, and 0.5% AgNPs and 2% CHX against E. faecalis. The results indicate that 2% CHX exhibits superior activity, while AgNPs at various concentrations also demonstrate inhibitory zones against E. faecalis.
根管冲洗剂可以抗击牙髓微生物菌群,有效针对粪肠球菌等顽固微生物,因为这些微生物在接受治疗后仍然存在。洗必泰(CHX)作为一种冲洗剂,具有广谱抗菌活性,在牙本质中具有显著的吸附性和良好的生物相容性。在纳米技术领域,银纳米粒子(AgNP)溶液具有很强的抗菌和抑菌特性,因此使用银纳米粒子溶液似乎很有前景。 本研究旨在比较不同浓度(1%、0.75% 和 0.5%)的 AgNPs 和 2% CHX 对粪肠球菌的抗菌效果。 本研究将评估四种冲洗溶液,包括 1%、0.75% 和 0.5% 的 AgNPs 和 2% CHX,并以庆大霉素作为对照。粪肠球菌的 ATCC 29212 菌株将在 37°C 下培养在脑心输液肉汤平板上。48 小时后,通过计数琼脂平板上的菌落形成单位来量化细菌数量。在平板上涂抹每种冲洗剂,并测量由此产生的细菌抑制区。 我们的研究证明了 1%、0.75%、0.5% AgNPs 和 2% CHX 对粪肠球菌的抗菌效果。虽然 2% CHX 表现出更高的活性,但不同浓度的 AgNPs 对粪大肠杆菌也有抑制作用。 总之,本研究强调了 1%、0.75%、0.5% AgNPs 和 2% CHX 对粪肠球菌的抗菌特性。结果表明,2% CHX 具有更强的活性,而不同浓度的 AgNPs 对粪大肠杆菌也有抑制作用。
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引用次数: 0
Harnessing the power of amnion-chorion membrane in periodontal therapy: A comprehensive review 在牙周治疗中利用羊膜-绒毛膜的力量:全面回顾
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_67_23
Ritu Agrawal, Aditya Sinha, S. S. Chauhan, Satendra Sharma
Amnion-chorion membrane (ACM) has emerged as a versatile biomaterial with immense potential in various medical and dental applications, including periodontal therapy. ACM possesses unique properties, including a bioactive matrix rich in growth factors, anti-inflammatory and antibacterial attributes, and a remarkably thin, self-adherent structure. These characteristics make ACM well suited for various periodontal applications, such as intrabony defect treatment, gingival recession management, socket preservation, papillary preservation, and sinus membrane repair. This review offers comprehensive details of the properties, applications, and implications of ACM membranes in the realm of periodontal treatment.
羊膜-绒毛膜(ACM)是一种多功能生物材料,在包括牙周治疗在内的各种医疗和牙科应用中具有巨大潜力。ACM 具有独特的特性,包括富含生长因子的生物活性基质、抗炎和抗菌特性,以及非常薄的自附着结构。这些特性使 ACM 非常适合各种牙周应用,如骨内缺损治疗、牙龈退缩管理、牙槽窝保存、乳头保存和窦膜修复。本综述全面详细地介绍了 ACM 膜在牙周治疗领域的特性、应用和影响。
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引用次数: 0
Dental auxiliaries’ knowledge, attitude, and practices regarding noma prevention: A cross-sectional study in Northwestern Nigeria 牙科辅助人员对预防坏疽性口炎的认识、态度和做法:尼日利亚西北部横断面研究
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_42_23
M. Bala, Muhammad Abubakar Kaura, Anas Bawa Tsafe, Rufai Jaafar, Sadeeq Abubakar Fawa, Ahmad Abdulkadir
The objective is to evaluate dental auxiliaries’ knowledge, attitudes, and practices for the prevention of noma disease. This was a cross-sectional study conducted over 6 months. After obtaining ethical clearance from the Sokoto and Zamfara State Ministries of Health, all consenting dental assistant staff who met the selection criteria were administered a validated questionnaire containing 17 questions assessing the respondents’ knowledge, attitudes, and practices. They were recruited using a self-administered questionnaire. The overall score was classified as “low” if the average score was 50% or less (50% or less), satisfactory (51%–69%), or good (70% or more). Data were analyzed using IBM SPSS version 20 software. A total of 149 respondents returned the questionnaire, of which 80 (53.7%) were men and 69 (46.3%) were women. The mean ± standard deviation age of respondents was 27.37 ± 7.00 years, with a range of 20–58 years. The age of respondents was divided into four groups, and the majority of 112 respondents (75.2%) were in their 30s. The majority of respondents, 141 (94.6%), know about the prevention of noma disease. The total respondent score was 1827 points (72.1%), which was evaluated as “good.” Knowledge, attitudes, and practices of dental auxiliaries in the field of noma prevention are good. Dental auxiliaries, if supervised and appropriately trained, can play a role in noma prevention by actively participating in and disseminating information on specific preventive measures such as scaling and polishing.
目的是评估牙科辅助人员在预防坏疽性口炎方面的知识、态度和做法。 这是一项横断面研究,为期 6 个月。在获得索科托州和赞法拉州卫生部的伦理许可后,对所有符合选择标准并同意的牙科助理人员进行了有效问卷调查,其中包含 17 个问题,用于评估受访者的知识、态度和做法。他们是通过自填问卷的方式招募的。如果平均得分在 50% 或以下(50% 或以下)、满意(51%-69%)或良好(70% 或以上),则总体得分被归类为 "低"。数据使用 IBM SPSS 20 版软件进行分析。 共有 149 名受访者交回了问卷,其中男性 80 人(53.7%),女性 69 人(46.3%)。受访者的平均年龄为 27.37±7.00 岁,年龄范围在 20-58 岁之间。受访者的年龄分为四组,112 名受访者中的大多数(75.2%)年龄在 30 岁左右。大多数受访者(141 人,占 94.6%)了解坏疽性口炎的预防知识。受访者的总得分为 1827 分(72.1%),评价为 "良好"。 牙科辅助人员在预防坏疽性口炎方面的知识、态度和做法良好。如果得到监督和适当培训,牙科辅助人员可通过积极参与和传播有关洗牙和抛光等具体预防措施的信息,在预防坏疽性口炎方面发挥作用。
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引用次数: 0
Evolution of orthodontic aligners: A narrative review 正畸矫治器的演变:叙述性综述
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_6_24
T. Nakhate, Suresh Kangane, Yatishkumar Joshi, Payal Brijlal Bhutada, Swathilekshmi Nair, Aavesh Bhoir
Clear aligners seem to be a new modality for patients undergoing orthodontic treatment; the initial concept of this treatment evolved in the 20th century. Remensnyder’s “Flex-O-Tite” appliance led to the introduction of the aligner, from this Kesling tooth positioner appliance made up of rubber-based 1945 proposed the concept of using it for minor tooth movements in a sequential series. The purpose of this article is to provide information about chronologically ordered evolution of aligners. Various types of generations and attachments used in different aligner systems. An online search was done using databases from PubMed and Google Scholar to find the articles. Database search was done with the following string: ((aligners [Title/Abstract]) AND (comparison [Title/Abstract])) AND (((fixed appliance [Title/Abstract]) OR (braces [Title/Abstract])) OR (fixed orthodontic appliance [Title/Abstract])). 3 articles are included in the narrative review to evaluate the better outcomes of the treatment effectiveness between fixed orthodontic treatment and aligners with short summary of chronological ordered evolution, generations and attachments of aligners. The overall effectiveness of orthodontic treatment depends upon the knowledge of clinician therefore knowledge about recent advances is important for proper treatment of the patient.
对于接受正畸治疗的患者来说,透明矫治器似乎是一种新的治疗方式;这种治疗方式的最初概念是在 20 世纪演变而来的。雷门斯奈德(Remensnyder)的 "Flex-O-Tite "矫治器导致了矫治器的问世,在此基础上,1945年由橡胶制成的凯斯林牙齿定位器(Kesling tooth positioner appliance)提出了使用矫治器进行一系列轻微牙齿移动的概念。本文旨在介绍按时间顺序排列的矫正器的演变过程。不同对齐器系统中使用的各代产品和附件类型。我们使用PubMed和Google Scholar数据库进行了在线搜索,以找到相关文章。数据库搜索使用了以下字符串:((对准器 [标题/摘要]) AND (比较 [标题/摘要]))AND (((fixed appliance [Title/Abstract]) OR (braces [Title/Abstract]))或(固定矫治器 [标题/摘要]))。叙述性综述中包括 3 篇文章,以评估固定正畸治疗和矫治器之间治疗效果的较佳结果,并对矫治器按时间顺序排列的演变、世代和附着情况进行了简短总结。正畸治疗的整体效果取决于临床医生的知识,因此了解最新进展对患者的正确治疗非常重要。
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引用次数: 0
Comparative evaluation of the differential staining ability of carbol fuchsin, methylene blue, and turmeric GC-MI paste between enamel and adhesive composite remnant after orthodontic debonding using a spectrophotometer 使用分光光度计比较评估正畸脱钩后珐琅质和粘合剂复合材料残留物之间的卡波紫素、亚甲蓝和姜黄 GC-MI 糊剂的不同染色能力
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_56_23
Sunil S Agrawal, Megha Jain, A. Chachada
After debonding, the primary concern of the clinician is to ensure the complete removal of the orthodontic adhesive composite remnant and restore the tooth surface to as near its original state as possible. However, the color resemblance of composite adhesive and enamel can increase the risk of tooth damage during debonding. To delineate composite from enamel, using various hydrophobic stains can be helpful in clean debonding. The aim of the present research was to assess and compare the differential staining ability of three stains, i.e., carbol fuchsin, methylene blue, and turmeric GC-MI paste, using a spectrophotometer. A total of 48 premolar samples were distributed among three groups, namely, Group A, Group B, and Group C. Each group of 16 samples was stained with carbol fuchsin, methylene blue, and turmeric GC-MI paste, respectively. The color value of enamel and composite was measured before and after staining by digital spectrophotometer using CIE L* a* b* scoring method. The mean difference color value of composite and enamel before and after staining was found to be 38.473 ∆ E, 17.211 ∆ E, and 18.715 ∆ E and 1.647 ∆ E, 1.297 ∆ E, and 1.293 ∆ E in Groups A, B, and C, respectively. The mean color value of composite and enamel was compared before and after staining using a t-test for all three groups and was found to be statistically highly significant. Carbol fuchsin, methylene blue, and turmeric GC-MI paste have the potential to be used as composite disclosing agents. Turmeric GC-MI paste appears to be a better agent as it stains composite effectively without significant staining on enamel.
脱粘之后,临床医生的首要任务是确保完全清除正畸粘合剂的复合残留物,并尽可能将牙齿表面恢复到接近原始状态。但是,复合粘合剂和珐琅质的颜色相似会增加脱粘过程中牙齿受损的风险。为了将复合树脂与珐琅质区分开来,使用各种疏水性染色剂有助于清洁脱粘。 本研究的目的是使用分光光度计评估和比较三种染色剂的不同染色能力,即卡波紫素、亚甲蓝和姜黄 GC-MI 糊剂。 48颗前磨牙样本被分成三组,即A组、B组和C组,每组16颗样本分别用石碳酸品红、亚甲基蓝和姜黄GC-MI糊剂染色。采用 CIE L* a* b* 评分法,用数字分光光度计测量染色前后珐琅质和复合材料的色值。 结果发现,A 组、B 组和 C 组复合材料和牙釉质染色前后的平均色差值分别为 38.473 ∆ E、17.211 ∆ E 和 18.715 ∆ E,以及 1.647 ∆ E、1.297 ∆ E 和 1.293 ∆ E。用 t 检验法比较了三组复合材料和珐琅质染色前后的平均色值,发现它们在统计学上具有高度显著性。 Carbol fuchsin、亚甲基蓝和姜黄 GC-MI 糊剂有可能用作复合材料的显色剂。姜黄 GC-MI 糊剂似乎是一种更好的制剂,因为它能有效地对复合材料进行染色,而不会对珐琅质造成明显的染色。
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引用次数: 0
Taurodontism in oral-facial-digital syndrome 口腔-面部-数字综合征中的牙髓病
Pub Date : 2024-07-01 DOI: 10.4103/jorr.jorr_10_23
Debasish Pramanick
Oro-facial-digital syndrome (OFDS) is one of the rare hereditary conditions involving various developmental anomalies of the oral cavity, face as well as digits. Oral-facial-digital syndrome, Type I (OFDS I), a variant of OFDS, is a X-linked dominant condition showing malformations involving the oral cavity, face, and digits, predominantly affecting the females and lethal in males. Taurodontism is a clinical condition rarely encountered in OFDS I. It is a tooth developmental anomaly caused due to the failure of Hertwig’s epithelial sheath to invaginate horizontally at proper level, thereby resulting in an enlarged pulpal chamber and apical displacement of the pulp floor. A case of OFDS I, with typical clinical findings along with a unique feature of taurodontism, is presented here. Performing root canal treatment in taurodontism is a challenge. An early diagnosis and treatment will help the patient to lead a normal and healthy life.
口腔-面部-数字综合征(OFDS)是一种罕见的遗传性疾病,涉及口腔、面部和手指的各种发育异常。口腔-面部-数字综合征 I 型(OFDS I)是口腔-面部-数字综合征的一种变异型,是一种 X 连锁显性遗传病,表现为涉及口腔、面部和手指的畸形,女性患者居多,男性患者致死。Taurodontism是一种在OFDS I中很少见的临床症状,它是由于Hertwig上皮鞘未能在适当水平水平内陷,从而导致髓腔扩大和髓底顶端移位引起的牙齿发育异常。本文介绍的一例 OFDS I 具有典型的临床表现和独特的牙髓病特征。对牙髓病进行根管治疗是一项挑战。早期诊断和治疗将有助于患者过上正常健康的生活。
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引用次数: 0
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Journal of Oral Research and Review
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