Research advances in targeted therapy of paclitaxel-induced neuropathic pain

The treatment of paclitaxel-induced neuropathic pain has been a research hotspot. Also, some progress has been made in the field of targeted therapy. In this article, we introduced paclitaxel, summarized the receptors or pathways that involved in pa-clitaxel-induced neuropathic pain, the characteristics of neuropathic pain that induced by paclitaxel, targeted treatment methods of pa-clitaxel-induced neuropathic pain and the progress of other treatment methods. By reviewing the targeted treatment methods of paclitax-el-induced neuropathic pain, we proposed and predicted other possible treatment methods in the future, explored the effective treatment methods of paclitaxel-induced neuropathic pain and provided possible basis for clinical treatment. Key words: Paclitaxel; Neuropathic pain; Targeted therapy