腹膜后巨大B细胞淋巴瘤伴慢性小肠梗阻1例报告

Ningi Ab, S. Aliyu, Adewunmi Ol, Zarami Ab
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摘要

腹膜后肿瘤是多种肿瘤病变的集合,以间质肿瘤为主。其他组织学类型,如淋巴瘤,据报道现在比较常见。腹膜后肿瘤通常是罕见的,临床诊断往往是困难的,由于其隐蔽性的位置。它通常在腹部放射学检查或并发症后偶然诊断。最常见的并发症是外源性压迫,特别是在腹膜后结构;如输尿管、十二指肠或腹部主要血管。它也可能表现为模糊的腹痛或慢性肠梗阻,就像我们的第一个病人一样。腹部CT扫描是最敏感的诊断工具,通常进行完整的手术切除,累及邻近器官的整体切除提供了最好的治愈机会。辅助化疗、放疗或放化疗可改善无病期和总生存期。然而,腹膜后淋巴瘤的主要治疗方法是细胞毒性化疗或最近的利妥昔单抗联合治疗。我们报告一例巨大的腹膜后大b细胞淋巴瘤,表现为慢性小肠梗阻。
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A Huge Retroperitoneal Large B-Cell Lymphoma Presenting as Chronic Small Bowel Obstruction: A Case Report
Retroperitoneal tumours are an aggregate of multiple types of neoplastic lesions with a preponderance of tumours of mesenchymal origin. Other histological types such as Lymphoma, are reported to be commoner now. Retroperitoneal tumours are generally rare and clinical diagnosis is often difficult due its cryptic location. It is often diagnosed incidentally following abdominal radiological studies or following complications. The most common complication being an extrinsic compression, particularly, on the retroperitoneal structures; such as the ureters, duodenum or the major abdominal vessels. It may also present as a vague abdominal pain or chronic bowel obstruction like our index patient. Abdominal CT Scan is the most sensitive tool of diagnosis and complete surgical excision often, an enbloc excision with involved adjoining organs offers the best chance of cure. Adjuvant chemotherapy, radiotherapy or chemo-radiation improve disease free interval and overall survival. The mainstay of retroperitoneal lymphoma is however a cytotoxic chemotherapy or more recently Rituximab combination therapy. We present a case of a huge retroperitoneal large B-cell Lymphoma presenting as chronic small bowel obstruction.
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