J. O. Rodríguez Velásquez, E. Prieto, C. E. Pérez Díaz, C. A. Valdés Cadena, G. F. Bulla, F. A. Barrios Arroyave, N. López, F. López
{"title":"基于HIV感染者白细胞总数的CD4+范围预测","authors":"J. O. Rodríguez Velásquez, E. Prieto, C. E. Pérez Díaz, C. A. Valdés Cadena, G. F. Bulla, F. A. Barrios Arroyave, N. López, F. López","doi":"10.22328/2077-9828-2022-14-4-67-72","DOIUrl":null,"url":null,"abstract":"Objective. To predict the amount of CD4+/μL3 in sequences of patient records with CD4 T lymphocyte values above 500 cells/μL3 and / or between 200 to 500 cells/μL3 from the absolute leukocyte count in the context of the theory of probability.Materials and methods. Two mathematical inductions were performed to find predictive mathematical relationships for CD4+/μL3 when they are above 500 cells/μL3 and between 200 to 500 cells/μL3, from the absolute count of leukocytes. Subsequently, the probability of success of the predictions was calculated, two blind studies were performed on 80 remaining data, and sensitivity and specificity were calculated for both cases.Results and discussion. If there are more than three records in time per patient, and these are above 500 CD4/μL3 cells or between 200 to 500 CD4/μL3 cells, finding that the absolute leukocyte count has a greater or equal value to three and lower to 4 for all the records, the following record will be maintained with a measurement of CD4 lymphocytes>500 or between [200, 500], if in the absolute count of leukocytes of the patient sequences a value of four is observed and CD4+ ranges from 200 to 500 cells/μL3, it can be deduced that there will be at least one measurement of CD4 +>500 cells/μL3 associated with a leukocyte measurement / μL3 greater than 3.7.Conclusions. We established two temporal mathematical patterns capable of predicting the CD4+/μL3 count from the absolute leukocyte count.","PeriodicalId":37381,"journal":{"name":"HIV Infection and Immunosuppressive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prediction of CD4+ ranges based on the total number of leukocytes in people living with HIV\",\"authors\":\"J. O. Rodríguez Velásquez, E. Prieto, C. E. Pérez Díaz, C. A. Valdés Cadena, G. F. Bulla, F. A. Barrios Arroyave, N. López, F. López\",\"doi\":\"10.22328/2077-9828-2022-14-4-67-72\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective. To predict the amount of CD4+/μL3 in sequences of patient records with CD4 T lymphocyte values above 500 cells/μL3 and / or between 200 to 500 cells/μL3 from the absolute leukocyte count in the context of the theory of probability.Materials and methods. Two mathematical inductions were performed to find predictive mathematical relationships for CD4+/μL3 when they are above 500 cells/μL3 and between 200 to 500 cells/μL3, from the absolute count of leukocytes. Subsequently, the probability of success of the predictions was calculated, two blind studies were performed on 80 remaining data, and sensitivity and specificity were calculated for both cases.Results and discussion. If there are more than three records in time per patient, and these are above 500 CD4/μL3 cells or between 200 to 500 CD4/μL3 cells, finding that the absolute leukocyte count has a greater or equal value to three and lower to 4 for all the records, the following record will be maintained with a measurement of CD4 lymphocytes>500 or between [200, 500], if in the absolute count of leukocytes of the patient sequences a value of four is observed and CD4+ ranges from 200 to 500 cells/μL3, it can be deduced that there will be at least one measurement of CD4 +>500 cells/μL3 associated with a leukocyte measurement / μL3 greater than 3.7.Conclusions. We established two temporal mathematical patterns capable of predicting the CD4+/μL3 count from the absolute leukocyte count.\",\"PeriodicalId\":37381,\"journal\":{\"name\":\"HIV Infection and Immunosuppressive Disorders\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HIV Infection and Immunosuppressive Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22328/2077-9828-2022-14-4-67-72\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HIV Infection and Immunosuppressive Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22328/2077-9828-2022-14-4-67-72","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Prediction of CD4+ ranges based on the total number of leukocytes in people living with HIV
Objective. To predict the amount of CD4+/μL3 in sequences of patient records with CD4 T lymphocyte values above 500 cells/μL3 and / or between 200 to 500 cells/μL3 from the absolute leukocyte count in the context of the theory of probability.Materials and methods. Two mathematical inductions were performed to find predictive mathematical relationships for CD4+/μL3 when they are above 500 cells/μL3 and between 200 to 500 cells/μL3, from the absolute count of leukocytes. Subsequently, the probability of success of the predictions was calculated, two blind studies were performed on 80 remaining data, and sensitivity and specificity were calculated for both cases.Results and discussion. If there are more than three records in time per patient, and these are above 500 CD4/μL3 cells or between 200 to 500 CD4/μL3 cells, finding that the absolute leukocyte count has a greater or equal value to three and lower to 4 for all the records, the following record will be maintained with a measurement of CD4 lymphocytes>500 or between [200, 500], if in the absolute count of leukocytes of the patient sequences a value of four is observed and CD4+ ranges from 200 to 500 cells/μL3, it can be deduced that there will be at least one measurement of CD4 +>500 cells/μL3 associated with a leukocyte measurement / μL3 greater than 3.7.Conclusions. We established two temporal mathematical patterns capable of predicting the CD4+/μL3 count from the absolute leukocyte count.
期刊介绍:
In the scientific-practical journal "HIV Infection and Immunosuppressive Disorders", published various issues of HIV medicine (epidemiology, molecular mechanisms of pathogenesis to the development of educational programs) leading scientists of Russia and countries of CIS, USA, as well as practical healthcare professionals working in research centers, research institutes, universities, clinics where done basic medical work. A special place on the pages of the publication is given to basic and clinical research, analytical reviews of contemporary and foreign reports, the provision of medical care for various diseases.