Gabriel Gatica-Bahamonde , Elizabeth Alexandra Godynyuk , Jessica Neicun , Emmert Roberts , Mehmet Mikail Tangerli , Robin van Kessel , Katarzyna Czabanowska , Keith Humphreys , Andres Roman-Urrestarazu
{"title":"利用基于废水的流行病学分析欧洲新型精神活性物质的使用趋势：系统综述","authors":"Gabriel Gatica-Bahamonde , Elizabeth Alexandra Godynyuk , Jessica Neicun , Emmert Roberts , Mehmet Mikail Tangerli , Robin van Kessel , Katarzyna Czabanowska , Keith Humphreys , Andres Roman-Urrestarazu","doi":"10.1016/j.etdah.2023.100053","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and Aims</h3><p>New psychoactive substances (NPS) pose challenges not only due to their harms to users but also because they are difficult to monitor with traditional epidemiologic methods. Wastewater-based epidemiology (WBE) offers a reliable method to assess drug-taking habits in different geographical settings and their evolution over time. The aim of this systematic review was to examine NPS preferences and trends across Europe.</p></div><div><h3>Methods</h3><p>We searched electronic databases between September 5th to 30th, 2022, included OVID/Embase, PubMed, Scopus, and Web of Knowledge. Key search terms focused on NPS, WBE, prevalence, and geographic Europe. 18 articles were included in the systematic review. All studies were WBE studies, with 17 studies collecting samples from wastewater treatment plants, one collecting from pissoirs. Due to heterogeneity across studies, a meta-analysis was not performed.</p></div><div><h3>Results</h3><p>Literature reviewed in this study showed a trend towards stimulant-type NPS use, with the United Kingdom showing highest detection frequency. The most detected chemical class of NPS were synthetic cathinones. Southern and Western Europe showed the largest variety of NPS detected. Metabolite detection ranged extensively across countries.</p></div><div><h3>Conclusion</h3><p>This is the first systematic review to address types of new psychoactive substances present in wastewater in Europe. Gaps in literature point to a need for standardization in wastewater-based epidemiology so that drug policies and public health policies, including drug and harm reduction services, can be targeted to those NPS that are most widely used.</p></div>","PeriodicalId":72899,"journal":{"name":"Emerging trends in drugs, addictions, and health","volume":"3 ","pages":"Article 100053"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysing the use trends of new psychoactive substances using wastewater-based epidemiology in Europe: A systematic review\",\"authors\":\"Gabriel Gatica-Bahamonde , Elizabeth Alexandra Godynyuk , Jessica Neicun , Emmert Roberts , Mehmet Mikail Tangerli , Robin van Kessel , Katarzyna Czabanowska , Keith Humphreys , Andres Roman-Urrestarazu\",\"doi\":\"10.1016/j.etdah.2023.100053\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background and Aims</h3><p>New psychoactive substances (NPS) pose challenges not only due to their harms to users but also because they are difficult to monitor with traditional epidemiologic methods. Wastewater-based epidemiology (WBE) offers a reliable method to assess drug-taking habits in different geographical settings and their evolution over time. The aim of this systematic review was to examine NPS preferences and trends across Europe.</p></div><div><h3>Methods</h3><p>We searched electronic databases between September 5th to 30th, 2022, included OVID/Embase, PubMed, Scopus, and Web of Knowledge. Key search terms focused on NPS, WBE, prevalence, and geographic Europe. 18 articles were included in the systematic review. All studies were WBE studies, with 17 studies collecting samples from wastewater treatment plants, one collecting from pissoirs. Due to heterogeneity across studies, a meta-analysis was not performed.</p></div><div><h3>Results</h3><p>Literature reviewed in this study showed a trend towards stimulant-type NPS use, with the United Kingdom showing highest detection frequency. The most detected chemical class of NPS were synthetic cathinones. Southern and Western Europe showed the largest variety of NPS detected. Metabolite detection ranged extensively across countries.</p></div><div><h3>Conclusion</h3><p>This is the first systematic review to address types of new psychoactive substances present in wastewater in Europe. Gaps in literature point to a need for standardization in wastewater-based epidemiology so that drug policies and public health policies, including drug and harm reduction services, can be targeted to those NPS that are most widely used.</p></div>\",\"PeriodicalId\":72899,\"journal\":{\"name\":\"Emerging trends in drugs, addictions, and health\",\"volume\":\"3 \",\"pages\":\"Article 100053\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Emerging trends in drugs, addictions, and health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667118223000041\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emerging trends in drugs, addictions, and health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667118223000041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景与目的新型精神活性物质不仅对使用者造成危害，而且难以用传统的流行病学方法进行监测。基于废水的流行病学(WBE)提供了一种可靠的方法来评估不同地理环境中的吸毒习惯及其随时间的演变。本系统综述的目的是检查整个欧洲的NPS偏好和趋势。方法检索OVID/Embase、PubMed、Scopus、Web of Knowledge等电子数据库，检索时间为2022年9月5日~ 30日。关键搜索词集中在NPS、WBE、患病率和地理欧洲。18篇文章被纳入系统综述。所有研究均为WBE研究，其中17项研究从污水处理厂收集样本，1项研究从污水处理厂收集样本。由于各研究存在异质性，未进行meta分析。结果本研究回顾的文献显示了兴奋剂型NPS的使用趋势，其中英国的检测频率最高。NPS中检出最多的化学类别为合成卡西酮类。南欧和西欧检测到的NPS品种最多。代谢物检测在各国范围广泛。结论本文首次对欧洲废水中存在的新型精神活性物质类型进行了系统综述。文献上的空白表明，需要对基于废水的流行病学进行标准化，以便药物政策和公共卫生政策，包括药物和减少伤害服务，能够针对那些使用最广泛的国家健康计划。
Analysing the use trends of new psychoactive substances using wastewater-based epidemiology in Europe: A systematic review
Background and Aims
New psychoactive substances (NPS) pose challenges not only due to their harms to users but also because they are difficult to monitor with traditional epidemiologic methods. Wastewater-based epidemiology (WBE) offers a reliable method to assess drug-taking habits in different geographical settings and their evolution over time. The aim of this systematic review was to examine NPS preferences and trends across Europe.
Methods
We searched electronic databases between September 5th to 30th, 2022, included OVID/Embase, PubMed, Scopus, and Web of Knowledge. Key search terms focused on NPS, WBE, prevalence, and geographic Europe. 18 articles were included in the systematic review. All studies were WBE studies, with 17 studies collecting samples from wastewater treatment plants, one collecting from pissoirs. Due to heterogeneity across studies, a meta-analysis was not performed.
Results
Literature reviewed in this study showed a trend towards stimulant-type NPS use, with the United Kingdom showing highest detection frequency. The most detected chemical class of NPS were synthetic cathinones. Southern and Western Europe showed the largest variety of NPS detected. Metabolite detection ranged extensively across countries.
Conclusion
This is the first systematic review to address types of new psychoactive substances present in wastewater in Europe. Gaps in literature point to a need for standardization in wastewater-based epidemiology so that drug policies and public health policies, including drug and harm reduction services, can be targeted to those NPS that are most widely used.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
