室上性心动过速患者消融后的生活质量与药物治疗

A. Mueed, Nandlal Rathi, Shahzad, Jibran Ashraf, S. Ahmed, L. Rai
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引用次数: 1

摘要

目的:室上性心动过速(SVT)是心脏急诊科患者最常见的表现。本研究旨在确定室上性心动过速患者在接受药物治疗和消融治疗后的生活质量。方法:这项前瞻性临床比较研究在国家心血管疾病研究所(NICVD)进行。18岁及以上的患者,不论性别,均有两种最常见的SVT变异,即房室结性再入性心动过速(AVNRT)和房室再入性心动过速(AVRT),符合纳入研究的条件。一旦在急诊科(ED)稳定下来,患者可以选择接受电生理研究和射频消融术(EPS和RFA) (A组)或选择仅接受药物治疗(B组)。生活质量(个人幸福感、对社交生活的影响、对死亡的恐惧或对疾病的焦虑、心律失常复发和ED就诊)在接受治疗六个月后通过填写问卷进行评估。结果:共纳入120例患者。A组和B组平均分为两组,每组60例。参与者的总体平均年龄和心脏病病程分别为44.67±18.91年和5.42±3.13年。接受EPS和RFA治疗的患者(A组)在个人幸福感、对社交生活的影响、对死亡或焦虑水平的恐惧、心律失常复发和急诊科就诊方面的得分(更好的生活质量)优于单独接受药物治疗的患者,p<0.05。结论:EPS和RFA治疗显著提高了SVT患者的生活质量。药物治疗本身与大量的治疗后后遗症和不良事件有关;因此,SVT患者最好避免使用。
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Quality of Life after Ablation vs Medication Therapy in Patients With Supraventricular Tachycardia
Objective: Supraventricular tachycardia (SVT) is the most common presentation of patients at cardiac emergency department. This study aims to determine the quality of life in patients with supraventricular tachycardia after they treated with medicines vs. ablation therapy. Methods: This prospective clinical comparative study was held at the National Institute of Cardiovascular Diseases (NICVD). Patients 18 years or older of either gender presenting with the two most common variants of SVT i.e. Atrioventricular nodal reentry tachycardia (AVNRT) and Atrioventricular reentry tachycardia (AVRT) were eligible to be included into the study. Once stabilized at the emergency department (ED) the patients were given the option to undergo electrophysiology study and radiofrequency ablation (EPS and RFA) (group A) or opt for medications only (group B). Quality of life (sense of personal well being, impact on social life, fear of mortality or anxiety about the disease, recurrence of episodes of arrhythmia, and visits to ED) was assessed through a questionnaire filled after six months of receiving treatment. Results: A total of 120 patients were included into our study. Group A and group B were evenly divided with 60 patients each. The overall mean age of the participants and duration of cardiac illness were 44.67±18.91 and 5.42±3.13 years, respectively. Patients who received EPS and RFA (group A) had superior and statistically significant scores (better QoL) for sense of personal well being, impact on social life, fear of mortality or anxiety levels, recurrence of arrhythmia, and visits to the ED as compared to those who received medications alone, p<0.05. Conclusion: EPS and RFA vastly improved the quality of life in patients with SVT post treatment. Medications alone are associated with a high number of post treatment sequels and adverse events; therefore they are best avoided in patients with SVT.
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