甲状旁腺腺瘤在BIRDEM综合医院的诊治体会

IF 0.1 Q4 OTORHINOLARYNGOLOGY Bangladesh Journal of Otorhinolaryngology Pub Date : 2021-04-28 DOI:10.3329/BJO.V27I1.53204
S. Mahbub, S. S. Biswas, B. K. Dey, S. Alam, J. Hoq
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引用次数: 0

摘要

背景:甲状旁腺瘤最常与原发性甲状旁腺功能亢进相关,甲状旁腺机能亢进导致高钙血症。高钙血症导致肾脏和胆道多发结石形成,提示手术切除肿瘤。围手术期的患者管理是预防死亡率和发病率的关键。本研究的目的是分析1例甲状旁腺瘤难治性患者,在术前、术中及术后对腺瘤进行定位,并采取措施维持正常钙水平。方法:回顾性研究于2017年5月至2019年12月在BIRDEM总医院和易卜拉欣医学院进行。我们对2017年5月至2019年12月在孟加拉国达卡BIRDEM总医院治疗的14例因甲状旁腺腺瘤被诊断为原发性甲状旁腺功能亢进的患者进行了回顾和纳入。结果:14例患者中,女性8例,男性6例(M: F=3:4)。年龄26 ~ 71岁,平均52岁。所有病例血清甲状旁腺激素(PTH)均高于正常水平(bbb65 pg/ml)。血钙高于正常12例(85.71%),正常2例(14.29%)。血清磷酸盐水平在正常范围内。所有病例均行腺瘤切除,并经术中冰冻切片证实。结论:成功治疗甲状旁腺瘤需要外科医生、内分泌学家、麻醉师和病理学家的综合技能。术后改善显著,疗效显著。孟加拉国J耳鼻咽喉;2021年4月;27 (1): 44-51
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Parathyroid Adenoma: an experience in BIRDEM General Hospital
Background: Parathyroid adenoma is most commonly associated with primary hyperparathyroidism which leads to hypercalcaemia. Hypercalcaemia results in multiple stone formation in Kidney and biliary tract which indicates surgical removal of tumor. Perioperative management of patient is essential to prevent mortality and morbidity. The purpose of this study is to analyze a case series of patient having parathyroid adenoma with difficulties, to localize the adenoma and to take the measures to maintain the normal level of calcium in pre, per and postoperative period. Methods: This retrospective study was carried out in BIRDEM General Hospital and Ibrahim Medical College from May 2017 to December 2019. 14 patients who were diagnosed as primary hyperparathyroidism due to parathyroid adenoma who had been managed at the BIRDEM General Hospital, Dhaka, Bangladesh from May 2017 to December 2019 were reviewed and included. Result: Among 14 patients 8 were female and 6 male (M: F=3:4). Age ranges from 26 to 71 years with mean age was 52 years. Serum PTH were above normal (>65 pg/ml) in all cases. Serum calcium level were above normal in 12 cases (85.71 %) and 2 (14.29%) had normal levels. Serum phosphate levels were within normal range. Excision of adenoma done in all cases which were confirmed by frozen section per-operatively. None of our patients develop any complication during and after surgery Conclusion: Successful management of parathyroid adenoma requires combined skills of surgeons, endocrinologists, anesthesiologists and pathologists. Improvement after operation is quite remarkable and rewarding. Bangladesh J Otorhinolaryngol; April 2021; 27(1): 44-51
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