COVID-19限制对糖尿病健康检查和2型糖尿病患者处方的影响:一项全英国队列研究,涉及618161名初级保健人员

M. Carr, A. Wright, L. Leelarathna, H. Thabit, N. Milne, N. Kanumilli, D. Ashcroft, M. Rutter
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引用次数: 45

摘要

目的比较2020年3月新冠肺炎首次高峰前后,2型糖尿病(T2D)患者执行国家卫生与护理卓越研究所推荐的健康检查和处方的比率,并评估趋势是否因年龄、性别、种族和剥夺而变化。方法我们研究了618 2020年3月至12月,从1744家在临床实践研究数据链接注册的英国全科诊所中,161名T2D患者接受了随访。我们重点进行了六项健康检查:血红蛋白A1c、血清肌酐、胆固醇、尿白蛋白排泄、血压和体重指数评估。回归模型将2020年4月和2020年3月至12月的观察到的利率与根据10年历史数据得出的趋势调整后的预期利率进行了比较。结果2020年4月,在英国诊所,进行健康检查的比率下降了76%-88% 与10年的历史趋势相比,贫困地区的老年人减少幅度最大。在2020年5月至12月期间,降低的利率逐渐恢复,但总体保持在28%-47% 更低,其他英国国家也有类似的发现。根据英国人口推断,2020年3月至12月的护理流程减少了约740万次。在英格兰,4月份新药的使用率下降,从抗血小板药物的10%(95%CI:4%-16%)到抗糖尿病药物的60%(95%CI:58%-62%)不等。总体而言,在2020年3月至12月期间,糖尿病新药的处方率下降了19%(95%置信区间:15%至22%),抗高血压新药的处方下降了22%(95%可信区间:18%至26%),但新的降脂或抗血小板疗法的处方没有变化。在英国各地也观察到了类似的趋势,除了英国其他国家新的降脂治疗处方减少(减少:16%(95%置信区间:10%至21%))。根据英国人口推断,在2020年3月至12月期间,约有31人 T2D患者开新型糖尿病药物的人数减少了800人,约14人 开了一种新型降压药的人减少了600人。结论在未来几个月,医疗服务部门将需要管理积压的检测和处方。我们建议进行有效的沟通,以确保患者参与糖尿病服务、监测和开处方的机会,并在适当的时候使用家庭监测、远程咨询和其他护理创新。
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Impact of COVID-19 restrictions on diabetes health checks and prescribing for people with type 2 diabetes: a UK-wide cohort study involving 618 161 people in primary care
Objective To compare rates of performing National Institute for Health and Care Excellence-recommended health checks and prescribing in people with type 2 diabetes (T2D), before and after the first COVID-19 peak in March 2020, and to assess whether trends varied by age, sex, ethnicity and deprivation. Methods We studied 618 161 people with T2D followed between March and December 2020 from 1744 UK general practices registered with the Clinical Practice Research Datalink. We focused on six health checks: haemoglobin A1c, serum creatinine, cholesterol, urinary albumin excretion, blood pressure and body mass index assessment. Regression models compared observed rates in April 2020 and between March and December 2020 with trend-adjusted expected rates derived from 10-year historical data. Results In April 2020, in English practices, rates of performing health checks were reduced by 76%–88% when compared with 10-year historical trends, with older people from deprived areas experiencing the greatest reductions. Between May and December 2020, the reduced rates recovered gradually but overall remained 28%–47% lower, with similar findings in other UK nations. Extrapolated to the UK population, there were ~7.4 million fewer care processes undertaken March–December 2020. In England, rates for new medication fell during April with reductions varying from 10% (95% CI: 4% to 16%) for antiplatelet agents to 60% (95% CI: 58% to 62%) for antidiabetic medications. Overall, between March and December 2020, the rate of prescribing new diabetes medications fell by 19% (95% CI: 15% to 22%) and new antihypertensive medication prescribing fell by 22% (95% CI: 18% to 26%), but prescribing of new lipid-lowering or antiplatelet therapy was unchanged. Similar trends were observed across the UK, except for a reduction in new lipid-lowering therapy prescribing in the other UK nations (reduction: 16% (95% CI: 10% to 21%)). Extrapolated to the UK population, between March and December 2020, there were ~31 800 fewer people with T2D prescribed a new type of diabetes medication and ~14 600 fewer prescribed a new type of antihypertensive medication. Conclusions Over the coming months, healthcare services will need to manage this backlog of testing and prescribing. We recommend effective communications to ensure patient engagement with diabetes services, monitoring and opportunities for prescribing, and when appropriate use of home monitoring, remote consultations and other innovations in care.
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Quality & Safety in Health Care
Quality & Safety in Health Care 医学-卫生保健
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