Arndt支气管内阻断剂和CO2人工胸腔积液用于婴幼儿单肺通气的比较

Guoliang Liu, Jianmin Zhang, Jia Gao, Wei Hao, Xiaoxue Wang
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摘要

目的比较Arndt支气管内膜阻断剂与CO2人工气相结合用于婴幼儿单肺通气的效果。方法选择28例6~36个月、美国麻醉师协会(ASA)Ⅰ级或Ⅱ级计划行胸腔镜检查的婴幼儿。全身麻醉诱导后,他们使用Arndt支气管内阻断剂或单腔气管插管,如果手术期间需要,可以单肺通气。根据病变肺塌陷方法的差异,根据随机数表法将他们分为两组(n=14):阿恩特支气管内阻断剂组(A组)和二氧化碳人工流产组(C组)。然后,我们观察并记录插管前(T1)、插管后(T2)、单肺通气开始时(T3)、单通气结束时(T4)和拔管时(T5)的平均动脉压(MAP)、心率和气道压力(Paw)的变化,并在手术期间的重要时间点进行血液分析以测量动脉氧分压(PaO2)和动脉二氧化碳分压(PaCO2)。我们还记录了肺塌陷程度、单肺通气时间、拔管时间以及围手术期缺氧(SpO2低于90%)的情况。结果所有患者均顺利完成手术。与C组相比,A组在T2、T4、T5时MAP和T4、T5 Paw均显著升高(P<0.05),其中1例因气管插管移位而缺氧,C组2例因长期胸压过高而缺氧。未发现严重不良反应。结论腔外应用Arndt支气管内阻断剂治疗婴幼儿单肺通气并发病变侧肺功能衰竭,与CO2人工流产相比,效果更好,血流动力学更稳定。关键词:婴儿;单肺通气;人工胸腔积液;纤维支气管镜;阿恩特支气管内阻断剂
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Comparison of extraluminal use of the Arndt endobronchial blocker and CO2 artificial pneumothorax for one lung ventila-tion in infants and children
Objective To compare the effects of extraluminal use of the Arndt endobronchial blocker and CO2 artificial pneu-mothorax for one lung ventilation in infants and children. Methods A total of 28 infants and children, aged from 6 to 36 months, American Society of Anesthesiologists (ASA) grades Ⅰ or Ⅱ , who were scheduled for thoracoscopy were selected. After induction of general anesthesia, they were placed with the Arndt endobronchial blocker or a single lumen tracheal tube, with one lung ventilation if needed during surgery. According to the differences in diseased lung collapse method, they were divided into two groups based on the random number table method (n=14): an Arndt endobronchial blocker group (group A) and a CO2 artificial pneumothorax group (group C). Then, we observed and recorded the changes of mean arterial pressure (MAP), heart rate, and airway pressure (Paw) before intuba-tion (T1), after intubation (T2), when one lung ventilation began (T3), when one lung ventilation ends (T4), and at the time of extubation(T5), and blood analysis was performed at important time points during surgery to measure arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2). We also recorded lung collapse degree, one lung ventilation time, extubation time, as well as the condition of perioperative hypoxia (with less than 90% of SpO2). Results Operation was successfully finished in all pa-tients. Compared with group C, group A presented remarkable increases in MAP at T2, T4 and T5 and Paw at T4 and T5 (P 0.05). There was one case of hypoxia due to tube displacement in group A. Two children in group C present-ed hypoxia due to excessive chest pressure for a long time. No serious adverse outcomes were found. Conclusions Compared with CO2 artificial pneumothorax, extraluminal use of the Arndt endobronchial blocker has better effects on lung collapse at the diseased side and more stable hemodynamics in infants and children with one lung ventilation. Key words: Infant; One lung ventilation; Artificial pneumothorax; Fiber bronchoscope; Arndt endobronchial blocker
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