赖氨酸受体基因对威尔士母猪繁殖特性的影响

IF 0.5 Q4 BIOLOGY Regulatory Mechanisms in Biosystems Pub Date : 2022-11-07 DOI:10.15421/022248
О. Zhukorskyi, О. М. Tsereniuk, P. Vashchenko, A. Khokhlov, Y. Chereuta, О. V. Akimov, N. V. Kryhina
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引用次数: 0

摘要

母猪的繁殖性能在很大程度上决定了整个养猪业的效率。我们工作的目的是评估赖氨酸受体基因的多态性及其对威尔士猪种母猪繁殖特性的影响。在这项研究中,使用了148头威尔士品种的猪。对相邻两代母猪的繁殖特性进行了评价。我们使用SIRQS(母猪繁殖质量选择指数)对母猪的繁殖能力进行了全面评估,确定了表型巩固系数,并评估了动物生产力的遗传潜力。应用聚合酶链式反应-限制性片段长度多态性分析(PCR-RFLP)测定RYR1基因的多态性。使用单因素方差分析(ANOVA)进行数据处理。对威尔士猪品种母猪ryanodine受体基因的多态性进行了评价。8.0%的动物被鉴定为RYR1基因的突变等位基因的携带者。然而,没有发现纯合的RYR1-nn动物。携带纯合NN基因型的母代猪在所有指标上都有更好的繁殖表现。与所有生产性状的整个估计群体相比,作为突变等位基因携带者的母猪的遗传生产力潜力值较低。没有RYR1基因突变等位基因的母猪的特征在于SIRQS指数的大值。没有突变等位基因的母猪的活产仔猪数量表型巩固系数低于有突变等位突变n的母猪。在所有评估的繁殖能力性状中,没有RYR1基因突变等位的母猪比携带RYR1基因的母猪表现更好(对于不同性状,P范围从0.021到1.0*10-4),除了在女儿一代中每头母猪活产的小猪数量。NN基因型母猪的选择指数在母代提高了15.7%,在女儿代提高了10.2%。为了提高所研究的威尔士猪群中母猪的繁殖能力,并在该品种的其他畜群中获得类似的结果,在繁殖过程中应选择不含RYR1基因突变等位基因的动物进行进一步繁殖,而相反,应逐渐从畜群中消除该基因的携带者。为了开展育种工作,需要对整个威尔士猪种群的RYR1基因进行进一步研究。
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The effect of the ryanodine receptor gene on the reproductive traits of Welsh sows
The reproductive performance of sows largely determines the efficiency of the entire pig farming industry. The purpose of our work is the evaluation of polymorphism of the ryanodine receptor gene and its impact on the reproductive traits of sows of the Welsh breed of pigs. For this study, 148 pigs of the Welsh breed were used. The reproductive traits of sows were evaluated in two adjacent generations. We conducted a comprehensive assessment of the reproductive ability of sows using the SIRQS (selection index of reproductive qualities of sows), determined phenotypic consolidation coefficients and assessed the genetic potential of the animals’ productivity. The polymorphism of the RYR1 gene was determined using polymerase chain reaction-restriction fragment length polymorphism analysis (PCR-RFLP). Data processing was performed using single-factor analysis of variance (ANOVA). Polymorphism of the ryanodine receptor gene in sows of the Welsh pig breed was evaluated. 8.0% of the animals were identified as carriers of the mutant allele of the RYR1 gene. However, no homozygous RYR1-nn animals were found. Pigs of the maternal generation carrying the homozygous NN genotype had better reproductive performance in all indicators. Sows that were carriers of the mutant allele were characterized by lower values of the genetic productivity potential compared with the entire estimated population for all productive traits. Sows which were free of the mutant allele of the RYR1 gene were characterized by large values of the SIRQS index. The values of the coefficients of phenotypic consolidation of the number of live born piglets in sows without the mutant allele were lower than in sows with the mutant allele n. Better performance of sows free of the mutant allele of the RYR1 gene was established over sows carrying it in all evaluated traits of reproductive capacity (for different traits P ranged from 0.021 to 1.0*10–4), except for number of piglets born alive per sow in the daughter generation. Sows with the NN genotype had better selection index values by 15.7% in the maternal generation and by 10.2% in the daughter generation. In order to increase the reproductive ability of sows in the studied population of Welsh pigs and achieve similar results in other herds of this breed, animals free from the mutant allele of the RYR1 gene should be selected for further reproduction in the process of breeding, while on the contrary, carriers of this gene should be gradually eliminated from the herd. To carry out breeding work, further research is needed on the entire population of Welsh pigs for the RYR1 gene.
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CiteScore
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发文量
25
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10 weeks
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