微波活化L-脯氨酸催化的有机反应

IF 0.9 Q4 CHEMISTRY, MULTIDISCIPLINARY Current Microwave Chemistry Pub Date : 2023-03-30 DOI:10.2174/2213335610666230330164520
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引用次数: 0

摘要

在过去的几年里,利用微波功率加热和处理化学反应已经成为科学界越来越受欢迎的课题。微波支持的有机合成被证实参与了具有选择性和增强生物活性的新型化合物的快速合成。用于化学合成的微波闪速加热显著缩短了反应时间,提高了产物的产率和纯度等。在催化领域,像L-脯氨酸这样的小有机分子是有效和选择性催化有机转化的。微波辅助L-脯氨酸催化反应是制备不同的无环、杂环和碳环支架的有价值的工具,这些支架是大多数生物活性化合物的主要骨架。在合成有机化学领域,微波辐射被多组分和分步合成化学领域的传统加热方法迅速抛弃。在这篇综述中,我们只讨论了在微波活化下使用现代有机转化的L-脯氨酸催化的有机反应,包括缩合、加成、不对称、多组分和其他模块化反应。
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L-Proline Catalyzed Organic Reactions via Microwave-Activation
In the past few years, using microwave power to heat and wield chemical reactions has become a gradually more popular subject in the scientific community. Microwave-supported organic synthesis is confirmed to be involved in the rapid synthesis of novel compounds with selectivity and enhanced biological activities. Microwave flash heating for chemical synthesis is a spectacular reduction in reaction times, high yield and purity of the products, etc. A catalysis field wherein small organic molecules like L-Proline is an efficiently and selectively catalyze organic transformations. Microwave-assisted L-Proline catalyzed reactions are valuable tools for the making of different acyclic, heterocycles, and carbocyclic scaffolds that signify the main framework of most of the bio-active compounds. The areas of synthetic organic chemistry, microwave irradiation is speedily discarded the conventional heating methods in the world of multicomponent as well as step-wise synthetic chemistry. In this review, we discuss only L-Proline Catalyzed Organic Reactions under microwave activation using modern organic transformations including condensation, addition, asymmetric, multi-components, and other modular reactions.
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来源期刊
Current Microwave Chemistry
Current Microwave Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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