睾酮改善美沙酮维持治疗患者的痛觉过敏

IF 0.4 Q4 NEUROSCIENCES Archives of Neuroscience Pub Date : 2022-01-30 DOI:10.5812/ans.121361

Nader Charkhgard, S. Naderi, Kamyar Ghani, Mahboubeh Manouchehrabadi

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引用次数: 0

摘要

简介:长期使用麻醉品会导致一些阿片类药物致痛觉过敏(OIH)的未知机制的患者出现痛觉过敏。病例介绍:一名43岁男性因长期使用美沙酮导致OIH综合征而服用睾酮。睾酮处方明显减轻痛觉过敏。结论:睾酮可能对OIH有治疗价值。

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Testosterone Improved Hyperalgesia in a Patient Under Methadone Maintenance Treatment

Introduction: Long-term use of narcotics causes hyperalgesia in some patients with an unknown mechanism known as opioid-induced hyperalgesia (OIH). Case Presentation: Testosterone was prescribed to a 43-year-old man suffering from the effects of OIH syndrome due to long-term use of methadone. Testosterone prescription significantly reduced the hyperalgesia. Conclusions: Testosterone may have a therapeutic value in OIH.

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Archives of Neuroscience NEUROSCIENCES-

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期刊介绍： Archives of neuroscience is a clinical and basic journal which is informative to all practitioners like Neurosurgeons, Neurologists, Psychiatrists, Neuroscientists. It is the official journal of Brain and Spinal Injury Research Center. The Major theme of this journal is to follow the path of scientific collaboration, spontaneity, and goodwill for the future, by providing up-to-date knowledge for the readers. The journal aims at covering different fields, as the name implies, ranging from research in basic and clinical sciences to core topics such as patient care, education, procuring and correct utilization of resources and bringing to limelight the cherished goals of the institute in providing a standard care for the physically disabled patients. This quarterly journal offers a venue for our researchers and scientists to vent their innovative and constructive research works. The scope of the journal is as far wide as the universe as being declared by the name of the journal, but our aim is to pursue our sacred goals in providing a panacea for the intractable ailments, which leave a psychological element in the daily life of such patients. This authoritative clinical and basic journal was founded by Professor Madjid Samii in 2012.