Vericiguat:药理学概况

Q4 Health Professions Klinicka Farmakologie a Farmacie Pub Date : 2022-07-07 DOI:10.36290/far.2022.013

K. Urbánek

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引用次数: 0

摘要

大约53%的给药剂量通过尿液排出，而45%通过粪便排出。健康志愿者的生物消除半衰期平均为20小时，心力衰竭患者的平均为30小时。其最常见的不良反应是低血压，发生率约为16%。它与药物相互作用的可能性很小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vericiguat: pharmacological profile

Approximately 53 % of the administered dose is excreted in the urine, while 45% in the faeces. The biological elimination half-life in healthy volunteers averaged 20 hours and in patients with heart failure averaged 30 hours. Its most common adverse effect with an incidence of about 16% is hypotension. It has minimal potential for drug interactions.

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来源期刊

Klinicka Farmakologie a Farmacie Health Professions-Pharmacy

CiteScore

0.30

自引率

0.00%

发文量