基于天然碳水化合物的纳米颗粒:药物应用综述

IF 0.7 Q4 CHEMISTRY, MEDICINAL Natural Products Journal Pub Date : 2022-08-26 DOI:10.2174/2210315512666220826145928
K. Kumar, Sheetu, Arun Sharma, Gurvinder Singh, Rajesh Kumar
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引用次数: 1

摘要

碳水化合物是最常见的生物聚合物,具有构建超分子结构的能力。为了生物医学目的,已经使用了各种基于碳水化合物的纳米颗粒。碱性单糖或二糖,以及复杂的聚合物系统,被用来产生这些结构。这些材料的形状和性能可以通过化学改变来改变。基于碳水化合物的纳米凝胶和纳米颗粒已被用于药物递送、组织工程和细胞成像。基于碳水化合物的元件是生产响应系统的优秀衍生物,因为组装的可逆特性通常基于疏水相互作用和氢键的混合物。本手稿试图回顾最近对碳水化合物基纳米材料的研究,以及对其专利的更新。
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Natural Carbohydrates-based Nanoparticles: A Review of Pharmaceutical Applications
Carbohydrates are the most common biopolymers, with the capability to construct supramolecular structures. For biomedical purposes, a variety of carbohydrate-based nanoparticles have been used. Basic monosaccharides or disaccharides, along with sophisticated polymeric systems, are used to create these structures. The shape and properties of these materials can be modified using chemical alterations. Carbohydrates-based nanogels and nanoparticles have been used for drug delivery, tissue engineering, and cell imaging. Carbohydrate-based elements are excellent derivatives for the production of responsive systems because of the reversible character of the assembly, which is frequently based on a mixture of hydrophobic interactions and hydrogen bonding. The present manuscript attempts to review the recent studies on carbohydrate-based nanomaterials and an update on the patents granted for the same.
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来源期刊
Natural Products Journal
Natural Products Journal CHEMISTRY, MEDICINAL-
CiteScore
1.70
自引率
0.00%
发文量
91
期刊介绍: The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.
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