Рathomorphological diagnosis of Pasteurellosis in fast-growing meet breeds of rabbits

Cite this article: Tishkina, N. M. & Tiupka, V. S. (2019). Рathomorphological diagnosis of Pasteurellosis in fast-growing meet breeds of rabbits. Theoretical and Applied Veterinary Medicine, 7(1), 36‒41. doi: 10.32819/2019.71007 Abstract. Genetically determined intensive growth and rapid increase rates of mass imported from abroad by the speedy breeds of rabbits of meat hybrid crosses affect the state of immunity of animals and their vital activity in general. In races for obtaining a quick profit in some farms there is an infringement of the conditions of keeping and feeding of animals, non-performance of zoohygienic and veterinary and sanitary standards, which leads to outbreaks of infectious diseases, among which the most common is pasteurellosis. Pasteurella infections remain the main cause of disease and mortality in commercial rabbits, which causes significant economic losses to owners. The results of the complex research of macroscopic and microscopic changes of the internal organs of rabbits by the action of pasteurellosis are presented. The pathologoanatomic autopsy was subjected to rabbits of the meat breed Hipplus with pre-established clinical diagnosis – pasteurellosis, grown in one of the private farms of the Dnipropetrovsk region. At the macroscopic level of the structural organization, pathological changes of the internal organs typical for the disease are detected – animal emaciation, hypodermic tissue edema and serous membranes, hemorrhages on the mucous and serous membranes of the internal organs, signs of catarrhal inflammation of the intestine, fibrinous – lungs, dystrophic symptoms in parenchymal organs. To confirm the diagnosis, the blood and smears-imprints of the organs for bacteriological examinations and the pieces of the internal organs – targets for pathologic and histologic examinations were sent to the laboratory. By the performed bacteriological examinations have been confirmed the presence of the causative agent – Pasteurella multocida. Microscopic analyzes are characterized by changes in the lungs and intestines during the acute course of the disease: signs of catarrhal and catarrhal hemorrhagic inflammation of the intestine and lungs, regional lymph nodes, granular and fatty dystrophy in the myocardium, liver and kidneys. In animals with a chronic course of the disease, thickening of the intestinal wall due to the enlargement of the connective tissue was observed. The villi of the mucous membrane had an irregular leaf form. Growth of the stroma, with a decrease in parenchyma in parenchymal organs are oberved.