多房囊性肾肿瘤-低恶性潜能(MCRN-LMP)综述

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引用次数: 1

摘要

低恶性潜能多室囊性肾肿瘤(MCRN-LMP),以前称为多房囊性肾细胞癌,是囊性肾的一种罕见变体。它由多个囊肿组成,由覆盖着透明细胞的薄隔膜分隔,没有膨胀性生长。术语MCRN LMP应仅用于识别囊性肾脏病变,囊壁中有一小簇肿瘤性透明细胞。临床上,这些病例可能表现为侧面疼痛,或者这些肿瘤中的大多数是在放射性成像中偶然发现的。大体上,肿瘤界限清楚,由多个不同大小的囊肿组成。纤维间隔通常很薄,没有明显的膨胀性结节。世界卫生组织/执行支助股的核等级一般较低,通常相当于1级或2级。在世界卫生组织(世界卫生组织)2016年对肾脏肿瘤的分类中,MCRN-LMP被认为是囊性肾脏的一种罕见变体。MCRN-LMP通常表现出TNM分类的低阶段。这些肿瘤有良好的临床病程。这些病变的临床过程表明,患者可能受益于保留肾单位的手术。这篇综述的目的是引起人们的注意,MCRN-LPM是一种低侵袭性肿瘤,没有复发和转移潜力。更新的诊断模式和保守的管理方针可能适用于这种罕见的实体,以更好地照顾患者。
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Multilocular cystic renal neoplasm-low malignant potential (MCRN-LMP) - review
Multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRN-LMP), previously known as multilocular cystic renal cell carcinoma as a rare variant of cystic kidney. It is composed of multiple cysts separated by thin septa covered with clear cells with no expansile growth. The termMCRN-LMPshould be used exclusively to identify a cystic kidney lesion with a small clusters of neoplastic clear cells in the cyst walls. Clinically these cases may present with flank pain or the majority of these tumors are incidentally found on radioimaging. Grossly, the tumor is well demarcated and consists of multiple various-sized cysts. The fibrous septa are generally thin and there is no discernible expansile nodule. The WHO/ISUP nuclear grade is generally low and usually corresponds to grade 1 or 2. In the World Health Organisation (WHO) 2016 classification of kidney tumors recognizes MCRN-LMP as a rare variant of cystic kidney. MCRN-LMP generally exhibits a low stage of TNM classification. These tumors have a favorable clinical course. The clinical course of these lesions suggests that patients may benefit from nephron-sparing surgery. The aim of this review is to bring attention, that MCRN-LPM is a low aggressive neoplasm with no recurrence and no metastatic potential. The updated diagnostic modalities and conservative line of management may be applicable for this rare entity for the better care of patients.
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