印度尼西亚与COVID-19疫苗副作用相关的因素

J. Wibowo, R. Heriyanto, F. Wijovi, D. A. Halim, C. Claudia, E. Marcella, B. Susanto, Michele Indrawan, Nadia Khoirunnisa Heryadi, Michelle Imanuelly, Jonathan Juniard Anurantha, T. Hariyanto, C.P.G.P.P. Marcellin, Terry Devita Sinaga, Saraswati Anindita Rizki, N. Sieto, J. Siregar, N. Lugito, A. Kurniawan
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引用次数: 5

摘要

随着2019冠状病毒病(COVID-19)继续迅速传播,在全球造成约1.86亿确诊病例,通过疫苗接种实现群体免疫的紧迫性日益增加。然而,疫苗安全性是限制不良事件发生的首要任务。因此,本研究的目的是在大流行期间认识和感知印度尼西亚的COVID-19疫苗安全性。材料和方法这是一项横断面研究,于2019冠状病毒病大流行期间在印度尼西亚进行,采用在线人口统计信息调查和定性问卷。对应答进行记录,并使用带有风险估计值和95%置信区间的卡方检验调查问题中人口学特征之间的关联。结果来自印尼34个省中的33个省共311名受试者参与了本研究。记录的反应显示,参与者经历了COVID-19疫苗的多种短期和长期副作用。人口统计学因素与COVID-19疫苗副作用有显著相关性,如女性性别与短期穿刺部位(优势比[OR], 0.463;95%可信区间[CI], 0.263-0.816)和短期其他反应(OR, 0.463;95% CI, 0.263-0.816),居住在爪哇岛以外,有长期穿刺部位(OR, 4.219;95% CI, 1.401-12.701)和免疫反应(OR, 3.375;95% CI, 1.356-8.398),婚姻状况与长期迷走神经反应之间也存在差异(OR, 4.655;95% ci, 1.321-16.409)。结论性别、户籍和婚姻状况因素与印尼人群COVID-19疫苗副作用相关。
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Factors associated with side effects of COVID-19 vaccine in Indonesia
Purpose As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic. Materials and Methods This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval. Results A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263–0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263–0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401–12.701) and immune reactions (OR, 3.375; 95% CI, 1.356–8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321–16.409). Conclusion Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
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来源期刊
CiteScore
3.70
自引率
3.70%
发文量
29
审稿时长
8 weeks
期刊介绍: Clin Exp Vaccine Res, the official English journal of the Korean Vaccine Society, is an international, peer reviewed, and open-access journal. It covers all areas related to vaccines and vaccination. Clin Exp Vaccine Res publishes editorials, review articles, special articles, original articles, case reports, brief communications, and correspondences covering a wide range of clinical and experimental subjects including vaccines and vaccination for human and animals against infectious diseases caused by viruses, bacteria, parasites and tumor. The scope of the journal is to disseminate information that may contribute to elaborate vaccine development and vaccination strategies targeting infectious diseases and tumors in human and animals. Relevant topics range from experimental approaches to (pre)clinical trials for the vaccine research based on, but not limited to, basic laboratory, translational, and (pre)clinical investigations, epidemiology of infectious diseases and progression of all aspects in the health related issues. It is published printed and open accessed online issues (https://ecevr.org) two times per year in 31 January and 31 July. Clin Exp Vaccine Res is linked to many international databases and is made freely available to institutions and individuals worldwide
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