雅加达住院肝硬化患者的生存分析:2年随访研究

R. Gani
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引用次数: 2

摘要

背景:印度尼西亚肝硬化的发病率随着时间的推移而增加。在这项研究中,我们的目标是使用Child-Pugh和MELD评分对肝硬化患者进行2年生存分析,并分析肝硬化患者最常见的死亡原因。方法:采用回顾性队列研究方法,对2011-2016年在Cipto Mangunkusumo医院内科病房就诊的患者病历进行评估。纳入标准是所有登记有完整病历的肝硬化患者。排除标准为存在肝细胞癌、胆管癌和其他形式的恶性肿瘤。结果:本研究共纳入89例患者。在2年随访期间,75.3%的患者死亡,最常见的死亡原因(COD)是感染(45.5%)。生存分析显示,肝硬化患者CP A级生存率明显优于B级和c级,2年死亡率临界值为CP评分bbb70分,MELD评分> 9分。结论:以感染为主要COD的肝硬化患者死亡率很高。Child-Pugh评分为B和C的患者预后较Child-Pugh评分为A的患者差。
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Survival Analysis of Hospitalized Liver Cirrhotic Patients in Jakarta: 2 Years Follow Up Study
Background: The incidence of liver cirrhosis in Indonesia is increasing over time. In this study, we aim to present a 2-year survival analysis on liver cirrhotic patients using Child-Pugh and MELD score and also analyzing the most common cause of death among liver cirrhotic patients. Method: A retrospective cohort study was used by evaluating the medical records of patients who went to internal medicine ward of Cipto Mangunkusumo Hospital during the period between 2011-2016. The inclusion criteria were all cirrhotic patient registered with a completely filled medical record. The exclusion criteria were the presence of Hepatocellular carcinoma, cholangiocarcinoma, and other form of malignancies Results: A total of 89 patients were included in this study. The total of 75.3% of the patients were dead during the 2 years follow up with the most prevalent cause of death (COD) being infection (45.5%). Survival analysis, showed that the survival of CP Class A were significantly better than B and C. The cut off value for 2-years mortality  was CP score > 7 and MELD score > 9 in liver cirrhotic patients Conclusion: The mortality rate of liver cirrhotic patients is very high with infection as the main COD. Patients with Child-Pugh score B and C have worse prognosis than Child-Pugh score A.
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发文量
42
审稿时长
8 weeks
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