The clinical value of ultrasound in the assessment of the severity of COVID-19

Objective: To summarize the ultrasound manifestations of lung lesions in patients with coronavirus disease 2019 (COVID-19), and explore the clinical value of ultrasonography in assessing the severity of the disease Methods: Thirty-one patients with COVID-19 admitted to the Fifth Affiliated Hospital of Sun Yat-sen University from January 18 to February 5, 2020, were selected as the research subjects All of them underwent dynamic lung ultrasound Their lung lesions were observed, and the lung ultrasound score (LUS) was performed, respectively The correlations between the LUS and the disease classification, the LUS and the blood oxygenation index (PaO2/FiO2) were analyzed, respectively The relationship between the corresponding change of clinical classification and the LUS score when it progressed to moderate/severe was analyzed as well Results: Among the 31 patients with COVID-19, two (6 5%) had no apparent lesions at the ultrasound, with the LUS score of 0 Twenty-nine (93 5%) showed abnormities at the ultrasound, with the LUS score from 1-26, and the main manifestations were B-line signs Among them 6 (19 4%) had the "white lung signs", and 13 (41 9%) had pulmonary consolidations The LUS score was positively correlated with the clinical classification (rs=0 683 2, P<0 001) and negatively correlated with PaO2/FiO2 (r=-0 864 3, P<0 001) In the initial and dynamic ultrasonography, 13 patients were graded as moderate/severe according to their LUS scores, and the accuracy of the LUS in assessing severe/critical patients was 81 3% (13/16) It was 1-3 days earlier for the LUS progressing to moderate/severe than clinical classification Conclusions: Pulmonary ultrasound manifestations of patients with COVID-19 have specific characteristics mainly showing as lung interstitial lesions, which can be combined with pulmonary consolidation Ultrasound can be used in the assessment of the severity of COVID-19 noninvasively and guide clinical treatment © 2020 Chinese Medical Association