Werner综合征或成人早衰症:一种罕见的模仿硬皮病的疾病

Jasleen Sandhu, Ankita Tuknayat
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引用次数: 0

摘要

沃纳综合征是一种早衰性疾病,是一种罕见的假性硬皮病的病因,可表现出多种临床特征,涉及皮肤、内分泌和心血管系统。虽然这种疾病是遗传性的,但它在青春期发病,皮肤特征如头发变白、皮肤萎缩硬化、复发性溃疡和色素沉着是首先表现出来的。所有这些特征通常会误导临床医生做出系统性硬化症的诊断。有人提出了一个类似的病例,并讨论了区分这两种疾病的重要性。
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Werner syndrome or adult progeria: a rare scleroderma mimicker
Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.
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