In Vitro Fertilization Pregnancy is One of the Risk Factor for Atonic Bleeding in Problem-Free Pregnancy

Background: To determine the risk factor for atonic bleeding in problem-free pregnancy. Methods: A total of 898 cases of problem-free singleton pregnancies that vaginal delivered at ≥ 37 weeks of gestation were divided into a two groups based on the total amount of bleeding two hours after delivery: 800 ml. The Mann-Whitney U-test was used for statistical analysis, and multivariate logistic regression analysis including the items showing a significant difference between the two groups was performed. Results: Three factors, infant weight [Adjusted odds ratio (AOR) 1.002; 95% CI 1.001-1.003, p<0.01], instrumental labor [AOR 3.406; 95% CI 1.933-5.896, p<0.01], and in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) pregnancy [AOR 2.071; 95% CI 1.157-3.611, p<0.01] increased the risk of bleeding over 800 ml. Conclusion: The instrumental labor and IVF/ICSI pregnancy increases the risk for atonic bleeding. It seems to be unrelated to other causes of bleeding related to these factors.