饮酒增加会延迟老年人认知障碍的诊断评估吗?

IF 1.4 Q4 CLINICAL NEUROLOGY Dementia and Geriatric Cognitive Disorders Extra Pub Date : 2022-02-07 DOI:10.1159/000521924
Ben Kamsvaag, K. Tevik, J. Šaltytė Benth, Bei Wu, S. Bergh, G. Selbaek, A. Helvik
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引用次数: 1

摘要

引言:从出现症状到评估认知障碍(TSA)的时间通常很长,许多因素会影响这一间隔的长度。我们的目的是了解饮酒量增加是否与TSA有关。方法:对3236名接受认知障碍评估的挪威老年人的饮酒量进行测量。高消费被定义为每周饮酒4-7次。TSA被定义为症状出现和评估之间的月数。通过对社会人口统计学和临床协变量进行控制的多元回归分析,检验了饮酒量与TSA之间的相关性。结果:平均(SD)和TSA中位数分别为34.8(35.8)和24.0个月。饮酒量增加与TSA无关。TSA时间较长与男性、高教育水平、退休或失业、单身、迷你精神状态检查(MMSE)或日常生活个人活动(PADL)得分低、神经精神问卷(NPI-Q)抑郁或躁动亚综合征得分高有关,或者有配偶/同居者作为指定的近亲。结论:本研究表明,饮酒量增加不会影响TSA。讨论了可能的解释,但还需要进一步的研究来确定酒精的影响。我们确实发现了与TSA相关的其他新特征,这些特征可能对最大限度地减少延迟认知评估的风险很重要,在考虑评估时应牢记。
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Does Elevated Alcohol Consumption Delay the Diagnostic Assessment of Cognitive Impairment among Older Adults?
Introduction: The time from symptom debut to assessment of cognitive impairment (TSA) is usually substantial, and many factors can influence the length of this interval. Our objective was to discern whether elevated alcohol consumption is associated with TSA. Methods: Alcohol consumption was measured among 3,236 older Norwegians assessed for cognitive impairment. Elevated consumption was defined as drinking 4–7 times a week. TSA was defined as the number of months between symptom debut and assessment. The association between alcohol consumption and TSA was examined with a multiple regression analysis controlled for sociodemographic and clinical covariates. Results: Mean (SD) and median TSA were 34.8 (35.8) and 24.0 months, respectively. Elevated alcohol consumption was not associated with TSA. Longer TSA was associated with being male, having a high education level, being retired or unemployed, being single, having low scores on the Mini-Mental State Examination (MMSE) or Personal Activities of Daily Living (PADL), having high subsyndrome scores of depression or agitation on The Neuropsychiatric Inventory – Questionnaire (NPI-Q), or having a spouse/cohabitant as the designated next of kin. Conclusion: This study indicates that elevated alcohol consumption does not influence TSA. Possible explanations are discussed, but further research is needed to determine the effect of alcohol definitively. We did identify other novel characteristics associated with TSA which may be important in minimizing the risk of delayed cognitive assessments and should be kept in mind when considering assessment.
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来源期刊
Dementia and Geriatric Cognitive Disorders Extra
Dementia and Geriatric Cognitive Disorders Extra Medicine-Psychiatry and Mental Health
CiteScore
4.30
自引率
0.00%
发文量
18
审稿时长
9 weeks
期刊介绍: This open access and online-only journal publishes original articles covering the entire spectrum of cognitive dysfunction such as Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field. Dementia and Geriatric Cognitive Disorders Extra provides additional contents based on reviewed and accepted submissions to the main journal Dementia and Geriatric Cognitive Disorders Extra .
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