南太平洋的糖尿病流行:在汤加利用握力的试点研究

Maria-Eleni Zioupos, J. Takai, Mehtab Ahmad, Peter Zioupos
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引用次数: 1

摘要

背景:手部握力(HGS)最近被证明有助于预测疾病结局和评估健康风险,特别是在心血管和代谢疾病中。研究证实了它与糖尿病(2型糖尿病)的联系,这表明它有可能被用作简单的筛查工具。这项研究在发展中国家的汤加糖尿病患者队列中检验了这种可能性。方法:在随机选择的患者队列中测量HGS,共149例患者,其中91例为T2DM, 58例为非T2DM。记录的其他测量数据包括患者人口统计、血压和糖尿病诊断日期。结果:各组HGS均随年龄增长而显著降低,且与男性BMI相关。使用“HGS”、“Age”和“BMI”建立二元logistic回归模型,灵敏度为82-84% (M/F),特异性为50-57%。结论:本研究使用T2DM的一个众所周知的影响和并发症,即患者受影响的握力,作为预测该疾病存在的“工具”参数,显示出非常好的敏感性。需要进一步研究该工具的更普遍的效用,而进一步的工作可能有助于在诊断中确定哪些人将受益于专业治疗。
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The Diabetes Epidemic in the South Pacific: A Pilot Study Utilising Hand Grip Strength in Tonga
Background: Hand-grip strength (HGS) has been shown recently to help in predicting disease outcomes and assessing health risk, particularly in cardiovascular and metabolic disease. Studies confirming its link to diabetes (T2DM) suggest there is potential for its use as simple screening tool. This study examined this possibility in a developing-world population, in a cohort of Tongan diabetics. Methods: HGS was measured in a randomly selected cohort of patients, comprising in total 149 patients, of which 91 with and 58 without T2DM. Other measurements recorded included patient demographics, blood pressure and date of diabetes diagnosis. Results: HGS was found to reduce significantly with age in all groups and it also related to BMI in males. Binary logistics regression models were produced using ‘HGS,’ ‘Age’ and ‘BMI’ which had a sensitivity of 82-84% (M/F) and specificity of 50-57%. Conclusions: This study uses one of the well-known effects and complications of T2DM, affected hand grip strength of sufferers, as a parameter in a ‘tool’ to predict the presence of the disease showing very good sensitivity. Further research is needed into the more general utility of the tool, while further work may help identify among the diagnosed those who would benefit from specialist treatment.
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